Total bilirubin, direct bilirubin, and indirect bilirubin are important indicators in liver function tests, and they are all associated with jaundice and liver function.
Total bilirubin is the sum of direct bilirubin and indirect bilirubin. Direct bilirubin, also known as conjugated bilirubin, is formed by the combination of unconjugated bilirubin with glucuronic acid, which is excreted mainly with bile. Indirect bilirubin, also known as unconjugated bilirubin, is produced by the catabolism of red blood cells and can be transported to the liver through the bloodstream, and then excreted through the uptake, transformation and excretion of hepatocytes.
Jaundice is a symptom of yellowing of the mucous membranes and sclera due to an increase in the level of bilirubin in the blood. Depending on the pathogenesis, jaundice can be divided into hemolytic jaundice, hepatocellular jaundice, and obstructive jaundice. Different types of jaundice have different pathogenesis and different methods.
Understanding the significance of total bilirubin, direct bilirubin, and indirect bilirubin is very important for the diagnosis and ** of jaundice. If you have any doubts or discomfort, please consult your doctor promptly. At the same time, you are welcome to subscribe, like, follow and ** in order to get more health information. Bilirubin