Ultima silicon wafer sequencing technology is a new milestone in genome sequencing

Mondo Science Updated on 2024-02-29

Genome sequencing has always been an important technology in medicine and science, and with the UG 100 ultra-high-throughput sequencing platform launched by Ultima Genomics, genome sequencing technology has ushered in a revolutionary revolution.

Ultima Genomics' UG 100 system utilizes silicon wafer sequencing technology, an innovative sequencing method. Compared to traditional flow cell methods, silicon wafer sequencing methods take a more economical and scalable approach. At the heart of the technology is the use of the large surface area of silicon wafers to generate dense electrostatic landing pad arrays through micron-scale patterns, combined with clonally amplified sequencing beads, to enable efficient genome sequencing. In addition, Ultima uses spin coating technology to quickly and evenly coat the surface of silicon wafers with reagents, further improving sequencing efficiency.

What stands out about this technology is its low cost and high accuracy. Each genome costs only about $100 and is accurate at one part per million. This means that even rare mutation events can be detected with a high degree of reliability, providing more accurate genomic information for diagnosis and **.

Dr. Gilad Almogy, CEO of Ultima, explained that the system is designed for large academic labs, genomic centers, and oncology and liquid biopsy companies. The introduction of this technology will open up more possibilities for applications such as tumor selection, minimal residual disease testing, and early screening of multiple cancers.

The introduction of silicon wafer sequencing technology marks an important breakthrough in the field of genome sequencing. With the continuous development and application of this technology, we have reason to believe that genome sequencing will become more economical and efficient, bringing more hope and possibilities for medical research and clinical diagnosis.

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