Transmembrane peptide mediates paclitaxel liposome|Peptidoglycan liposomes.
Name: Transmembrane peptide-mediated paclitaxel liposome.
Purity: 95%+
Storage conditions: -20°C, protect from light and moisture.
Transmembrane peptide-mediated paclitaxel liposomes may refer to a formulation that encapsulates paclitaxel in liposomes using a specific transmembrane peptide as a carrier. Transmembrane peptides can help improve the intracellular uptake and permeability of drugs.
The steps to prepare transmembrane peptide-mediated paclitaxel liposomes may include:
Liposome preparation: Liposome preparation is carried out by selecting appropriate liposome components, such as phospholipids and cholesterol, by suitable methods (e.g., membrane ultrafiltration, emulsification, membrane lysis-co-precipitation, etc.).
Membrane-permeable peptide design and synthesis: Design and synthesis of peptides with membrane-permeable properties that can help drugs better cross cell membranes.
Paclitaxel loading: Paclitaxel is loaded into the liposome, ensuring its uniform distribution.
Transmembrane peptide guidance: Transmembrane peptide guidance is attached to the liposome surface to increase the orientation of the drug to the cell.
Characterization of the prepared transmembrane peptide-mediated paclitaxel liposomes, including particle size distribution, drug encapsulation efficiency, etc.
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It is for scientific research only and cannot be used for human experiments2024.02.01