Bifunctional RGD-TAT peptide-modified liposomes, RGD-TAT-LPS
Name: RGD-TAT peptide modified liposomes (RGD-TAT-LPS).
Purity: 95%+
Storage conditions: -20°C, protect from light and moisture.
Purpose: Scientific research.
Condition: Solid powder solution.
Bifunctional RGD-TAT peptide-modified liposomes (RGD-TAT-LPS) are a two-functional nanocarrier system. Such systems typically contain two functional peptides: RGD peptides and TAT peptides.
RGD Peptide: RGD is a peptide sequence of three amino acids (arginine-glycine-aspartic acid) that normally binds to V3 integrins on the cell surface. This integrin is overexpressed on the surface of many cancer cells, so RGD peptides can act as ligands to target tumor cells.
TAT peptide: TAT peptide (trans-activator of transcription peptide) is a membrane-penetrating peptide derived from human immunodeficiency virus (HIV), which has the ability to penetrate the membrane and promote the entry of substances loaded with TAT peptide into cells. Therefore, the introduction of TAT peptides into the surface of liposomes can enhance their ability to penetrate cell membranes and improve the intracellular delivery efficiency of drugs.
Bifunctional liposomes with RGD and TAT peptides are often achieved by chemical synthesis or modification of the liposome surface. The preparation process may include steps such as the preparation of liposomes, the synthesis or extraction of RGD-Tat peptides, and the modification of liposome surfaces.
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It is for scientific research only and cannot be used for human experiments2024.02.01