In the IVF process, many patients may be notified to cancel the fresh embryo transfer after egg retrieval, and the doctor will instruct: "Freeze the embryo first, wait for the next cycle and then carry out the frozen embryo transfer." ”
Is there a disappointment mixed with a hint of doubt: why can't I transfer fresh embryos? Is it better to transfer frozen embryos than fresh embryos?
What are the conditions under which a fresh embryo transfer cannot be performed?
Due to ovulation induction, the endometrium of many women at this time is in a state of supraphysiological hormone action, and sometimes it is not suitable for embryo implantation; Or because of the higher risk of ovarian hyperstimulation, the doctor may also recommend the option of whole embryo freezing. There are several reasons for this:
Embryonic factors. The laboratory evaluates embryo quality based on the morphology of the embryo, such as the proportion of embryo fragments, the uniformity of blastomeres, the multinucleation, and the number of cleavage cells. If the quality of the embryo is not up to par, the transfer will be cancelled.
Intimal factors. The most suitable condition for embryo implantation is that the endometrium thickness is 8-16mm, and the echo is uniform and the blood flow is normal, indicating that the endometrium has good tolerance at this time and has a high probability of successful implantation after transplantation. If there are polyps, fibroids, too thick or too thin, slow blood flow and other problems of the lining, it is not conducive to embryo implantation and development.
Progesterone values are elevated.
Progesterone-induced transformation of endometrial morphology to secretory phase is a necessary condition for implantation, and when progesterone rises on the day of hcg, the endometrial implantation window will be opened in advance, resulting in the non-synchronization of embryonic and endometrial development in some patients, and it is recommended that patients abandon cycle transfer in this case.
Ovarian hyperstimulation syndrome (OHSS).
Ovarian hyperstimulation syndrome is an iatrogenic complication that occurs during the luteal phase after ovulation induction or in the first trimester of pregnancy, and is most likely to occur in young, thin patients with polycystic ovary syndrome.
For these high-risk groups, doctors develop standardized interventions in terms of program development, drug use, dietary guidance, and weight control. If the patient cooperates, the risk of ovarian hyperstimulation syndrome can be greatly reduced, and the transplant will not need to be canceled.
Hydrosalpinx.
The main mechanisms of hydrosalpinx affecting pregnancy are the mechanical scouring of the embryo by hydrosalpinx, and the toxic effect of inflammatory substances in hydrosalpinx on the embryo. Moreover, it is a liquid composed of toxic and harmful components, if the fluid is poured into the uterine cavity, it will cause harm to the embryo, which will make it difficult to implant and affect the normal growth and development.
Other reasons. During the transfer period, patients with fever, infection, poor control of chronic diseases, abnormal indicators of laboratory tests, or excessive psychological pressure will also have adverse effects on embryo implantation and subsequent development, and the fresh embryo transfer will generally be cancelled.
When it comes to canceling a transplant, you don't have to feel anxious and depressed, and you should wait for the best time for transplantation.
Remember, stop for a better start!