Embryo transfer is one of the core links in the IVF process of assisted conception, and it is not easy to get to the step of embryo transfer.
So, who is better in terms of PK in the pregnancy rate of fresh embryos and frozen embryos?
Fresh vs frozen.
In vitro treatment, embryos are mainly divided into two forms, one is fresh embryos and the other is frozen and thawed embryos.
Fresh embryos. Fresh embryo transfer is generally a direct transfer of D3 embryos (embryos cultured to day 3) or day 5 blastocysts (embryos cultured to day 5) directly into the body, and this process does not involve the operation of freezing embryos.
If there are no abnormal factors in the uterine cavity and the mother's body, doctors usually recommend fresh embryo (cleavage stage or blastocyst stage) transfer, which not only shortens the time of IVF**, but also relieves the anxiety and stress of long-term infertility.
A more limiting point is that the pregnancy rate of embryo transfer may be affected by the stimulation regimen, or the uterine environment, hydrosalpinx, and ovarian recovery after egg retrieval.
Therefore, fresh embryo transfer needs to be carried out after a detailed assessment of the physical condition.
Frozen embryo transfer. For a variety of reasons, embryos stored in liquid nitrogen in -196 by freezing technology are referred to as frozen embryos. Embryo freezing is usually chosen when patients have ovarian hyperstimulation and other physical reasons that are not suitable for fresh embryo transfer.
The cryopreserved embryos contain both the cleavage embryo of D3 and the blastocyst of D5.
Compared with fresh embryo transfer, frozen embryo transfer has more time to regulate the body, such as hydrosalpinx, uterine lesions, ovarian hyperstimulation syndrome, etc., which can be treated for the ** that affects pregnancy, so it is also more advantageous in terms of physical conditions.
For various reasons, if you choose to preserve embryos for frozen embryo transfer, some of the costs will increase accordingly after the cycle is extended.
Which embryo has a higher pregnancy rate?
1.In terms of embryo quality.
Whether it is fresh embryos or frozen embryos, they are the same batch of sperm and eggs, and there will not be much difference in quality; And it is also the best quality embryos for transfer after laboratory rating, and of course there will be no difference in pregnancy rate.
2.On its own terms.
Both frozen and fresh embryo transfers require careful evaluation of factors such as the uterine environment and hormone levels to ensure that the body is physically fit to receive the embryos. While frozen embryo transfer requires some period of conditioning, it can also be performed after the body is ready, which helps to ensure the best timing for the transfer. Fresh embryo transfer, on the other hand, is performed immediately after embryo formation, but it also requires a detailed assessment to ensure success. Therefore, there is no significant difference between the two methods in terms of physical condition, and it is important to choose the best method that is suitable for the individual situation.
Summary: There is no significant difference in pregnancy rates between fresh and frozen embryos.
All in all, whether transferring fresh or frozen embryos, ensuring good physical condition is essential to increase pregnancy rates. Good physical condition can include aspects such as a healthy lifestyle, a reasonable diet, adequate rest, and a balanced mental state. In addition, the doctor may advise the patient to take some auxiliary measures, such as taking nutritional supplements, physical conditioning, or reducing stress, to further improve the chances of a successful pregnancy.