The end of the year is approaching, all kinds of parties are overwhelmed, drinking is essential, but sometimes it is really impossible to drink: I drove the car, I have an upset stomach, I have a cold and eat cephalosporin......
"Cephalosporin wine" may have adverse effects.
On the afternoon of February 4, a talk show actor Yang Bo posted on his personal Weibo that he was suspected of committing suicide, which attracted attention. Subsequently, he was found to be not in danger of life, but his response once again sparked heated discussions on the Internet. He said, "Don't worry, everyone, I'm fine, I found that cephalosporin can't die at all when I drink alcohol, except for a little upset stomach, nothing at all." As soon as the remarks of "cephalosporin can't die at all when drinking alcohol" came out, many netizens couldn't sit still: "Cephalosporin is drunk, just leave" that everyone has heard for a long time, is it fake?
On February 5, the reporter interviewed Wu Dong, an emergency physician at Shaanxi Provincial People's Hospital, and learned that the warning about "eating cephalosporin and not drinking alcohol" is not groundless.
Cephalosporin is a common antibiotic and is widely used in a variety of infections. When cephalosporin meets wine, the two may have an adverse reaction called the disulfiram reaction. What is Disulfiram Reaction? Wu Dong said that the reaction caused by drinking alcohol after taking medicine is called the disulfiram reaction. Disulfiram itself is a kind of alcohol withdrawal drug, disulfiram can inhibit the acetaldehyde dehydrogenase in the liver when combined with ethanol, so that after the ethanol is oxidized to acetaldehyde in the body, it can no longer continue to decompose and oxidize, resulting in the accumulation of acetaldehyde in the body and a series of reactions. These reactions may include facial flushing, conjunctival hyperemia, blurred vision, throbbing of blood vessels in the head and neck or throbbing headache, dizziness, nausea, vomiting, sweating, dry mouth, chest pain, myocardial infarction, acute heart failure, dyspnea, acute liver injury, convulsions, and death.
Cephalosporin is alcohol, just go", so many people mistakenly think that this combination has some death-seeking function, but in fact, the severity of symptoms is directly proportional to the amount of alcohol consumed, the time and the amount of medication taken. At the same time, the severity of the disulfiram-like reaction is also related to the individual's metabolic capacity, Wu Dong said. For example, in the talk show actor, the disulfiram-like reaction is specifically manifested as "except for a little stomach discomfort, nothing at all". "The saying that cephalosporin is alcohol, just go" is a bit absolute, but it is indeed dangerous to take cephalosporin after drinking alcohol or drink alcohol after taking cephalosporin, and there are indeed fatal cases. Wu Dong said.
It is recommended to drink alcohol after 7 days of eating cephalosporin.
After this incident, Weibo's 2021 Top Ten Influential Health and Medical Vs "Doctor Do" also urgently spoke, "Please don't mislead others!" Just because you're okay doesn't mean that others are okay if they eat cephalosporin and drink alcohol. Survivorship bias is not an example of how lucky everyone is. Dr. Do said that the gastrointestinal discomfort described in the response may be one of the disulfiram-like reactions caused by alcohol consumption after taking cephalosporin antibiotics. "As a doctor, once again, I implore everyone not to drink alcohol after eating cephalosporin, you never know if you are the lucky one. ”
So, how long after eating cephalosporin can I drink alcohol? Wu Dong said that the medical community generally believes that if you eat cephalosporin first, it is recommended to drink alcohol after 7 days of medication to ensure that all the drugs in the body are metabolized. Another situation is that after drinking alcohol first, it is more appropriate to eat cephalosporin after 3 days, because for most people, alcohol is almost completely metabolized after 3 days. "Although you can take medicine 3 days after drinking, or you can drink alcohol after 7 days of taking medicine, there are special cases where disulfiram reactions can still occur, so try not to drink alcohol and don't become a special case for statistics. Wu Dong said.
Wu Dong reminded that once the symptoms of disulfiram reaction appear, you should stop drinking alcohol immediately and seek medical attention immediately. Before waiting for first responders to arrive, the following measures can be taken: keep the air circulating; If there is an exercise bracelet, it can be used to detect heart rate and oxygen saturation; For patients who vomit persistently, they need to lie flat with their head tilted to one side to avoid aspiration.
The reporter learned from the interview that in addition to cephalosporins, there are also nitroimidazoles (such as metronidazole, etc.), quinolones (such as levofloxacin, etc.) antibiotics are also prone to disulfiram reaction. In addition, although you do not drink alcohol, you should also avoid eating alcoholic foods at the same time, such as chocolate, egg yolk pie, mash, braised pork, etc.
During the Spring Festival, relatives and friends gather, although drinking can create an atmosphere, Wu Dong reminds everyone that we must remember: take medicine and don't drink alcohol, drink alcohol and don't take medicine, so as not to be happy and sad.
Xi'an newspaper reporter Ma Xiang.