How can mold in a pharmaceutical workshop be completely eliminated? How to solve mold contamination in the GMP workshop.
The pharmaceutical industry has very high requirements for the quality and safety of products, and mold is one of the common problems in pharmaceutical workshops. Mold can lead to product contamination, affecting the quality and safety of the product. Therefore, it is very important for pharmaceutical workshops to completely eliminate mold. This article will introduce the hazards of mold in pharmaceutical workshops, how to completely eliminate mold, and how to solve problems such as mold contamination in GMP workshops.
1. The hazards of mold in pharmaceutical workshops.
Mold is a common microorganism that grows and multiplies easily in the environment of pharmaceutical workshops. The presence of mold can adversely affect the pharmaceutical production process and product quality. The following are the hazards of mold to pharmaceutical workshops:
1.Product contamination: Mold can contaminate items such as pharmaceutical equipment, tools, containers, etc., which in turn can lead to product contamination. This not only affects the quality and safety of the product, but also poses a potential threat to the health of patients.
2.Production delays: If mold in a pharmaceutical shop is not controlled in a timely manner, it can lead to interruptions in the production process. Because equipment needs to be cleaned and repaired, and even parts need to be replaced, this will lead to increased production costs and delays in production time.
3.Harm to employee health: Mold releases spores in the air that can cause allergic reactions and respiratory problems when inhaled by employees, and even cause employees to become ill. This not only affects the physical health of employees, but also has a negative impact on the company's productivity and reputation.
2. How to completely eliminate mold in the pharmaceutical workshop.
In order to ensure the quality and safety of pharmaceutical products, effective measures must be taken to completely eradicate mold in pharmaceutical workshops. Here's how to get rid of mold:
1.Cleaning and disinfection: Cleaning is the foundation of mold eradication. Pharmaceutical workshops should be cleaned daily, and equipment, tools, containers and other items should also be cleaned thoroughly on a regular basis. In addition to cleaning, it is also necessary to disinfect the pharmaceutical workshop with a disinfectant with a bactericidal effect to kill the remaining mold and spores.
2.Control of ambient humidity and temperature: The growth and reproduction of mold requires certain humidity and temperature conditions. Therefore, pharmaceutical workshops need to control the humidity and temperature of the environment so that it is not conducive to the growth and reproduction of mold. For example, measures such as a dehumidifier can be used to reduce indoor humidity, and an air conditioning system can be used to control the temperature.
3.Regular inspection and monitoring: In order to ensure that the hygiene of the pharmaceutical workshop meets the requirements, the workshop needs to be regularly inspected and monitored. Professional mold detection reagents or instruments can be used for inspection, so that problems can be found and dealt with in time.
4.Establish a health management system: Establishing a sound health management system is one of the important measures to eliminate mold in pharmaceutical workshops. The system should clarify the requirements and processes for cleaning, disinfection, inspection, etc., and require employees to strictly comply with them.
5.Training and education: Employees are the main body of the pharmaceutical workshop, and their behavior and awareness directly affect the hygiene of the workshop. Therefore, it is necessary to train and educate employees so that they understand the hazards of mold and how to prevent it, improve hygiene awareness, and consciously comply with the hygiene management system.
3. How to solve mold pollution in GMP workshop.
GMP (Good Manufacturing Practice) is one of the important regulations in the pharmaceutical industry, which puts forward higher requirements for the hygiene and safety of pharmaceutical workshops. In the GMP workshop, tackling mold contamination requires more stringent measures:
1.Establish an air purification system: The GMP workshop should establish an air purification system to filter and disinfect the air entering the workshop to ensure that the quality of the air meets the requirements. At the same time, the exhaust air of the workshop needs to be filtered and disinfected to prevent the mold spores from being discharged outside and causing pollution.
2.Strict control of logistics: GMP workshop should be strictly controlled and logistics to reduce the risk of pollution.
Fourth, a new solution suitable for removing mold contamination in GMP workshop
Among them, sterilization refers to the killing of all microorganisms in the space (including bacterial spores), many enterprises choose such as: ozone fumigation, formaldehyde fumigation, propylene glycol lactic acid fumigation, vaporized hydrogen peroxide, etc., but in the process of sterilization and disinfection, there are a small number of disadvantages to different degrees, and our company in order to respond to the sterilization requirements of many domestic space disinfection, especially the aseptic workshop in the clean area, and at the same time to deal with the domestic GMP imported advanced sterilization equipment and sterilization reagents from abroad, And in this way, we can tailor a professional sterilization plan for customers.
Solution: Nuofu brand sporicide imported from Belgium + Orpheum dry mist hydrogen peroxide sterilization equipment. Our dry mist sterilization program is currently the most suitable method for domestic GMP manufacturers to pass the verification, at present, there are more than 200 stable customers in the pharmaceutical industry, Nuofu space sporicide needs to cooperate with Orpheum dry mist hydrogen peroxide sterilization equipment to complete, through the unique dry mist technology, the hydrogen peroxide sporicide particles are beaten into 5 micron particles to form a gaseous state, so as to achieve the killing rate of 6 logarithmic values of Bacillus subtilis, proud of all competitors in the world!
The advantages of dry mist hydrogen peroxide are summarized as:
1. Efficient killing of spores.
2. Completely replace formaldehyde, and at the same time, the time is short, and only 2 hours of sterilization time can be started.
3. The verification data is complete, and the residue, compatibility, and sterilization effect (scheme) can be provided.
4. Flexibility, which is the biggest feature, can be widely used in various clean areas of pharmaceutical enterprises, including laboratories, material rooms, core filling rooms, etc., because the sterilization process is short, so it can be simply used in various spaces, which greatly saves costs and workload.
5. The corrosiveness is small, even if the same concentration of sporicide, compared with surface wiping and dry fog fumigation, our dry fog fumigation equipment is much less corrosive, you can refer to the "Compatibility Verification Instructions".
6. The cost is very low, compared with the current gaseous hydrogen peroxide, we are only 20 to 30 of them, which is the most cost-effective for enterprises that use ozone every day and consume a large amount every month.
Runlian is familiar with GMP specifications, complete verification data, professional in pharmaceutical disinfection experience, writing verification documents and reports and efficacy test verification practice, only the sporicide that has passed the quality verification is the product that the pharmaceutical factory can rest assured. For more information, please contact Runlian Wanggong: 18922878167 the same number on WeChat