Phospholipid polyethylene glycol trans cyclooctene DSPE PEG TCO MW 2000

Mondo Health Updated on 2024-02-19

Product name: Polymer PEG derivative phospholipid polyethylene glycol trans-cyclooctene.

Product Name: DSPE-PEG-TCO,MW: 2000

The polymer PEG derivative DSPE-PEG-TCO is a compound containing phospholipid molecules DSPE and polyethylene glycol PEG, as well as a functional group of TCO**-cyclooctenyl).

DSPE: 1,2-distearoyl-sn-glycero-3-phosphatidylcholine, is a phospholipid molecule commonly used in the construction of nanoparticles or liposomes, with a dialkyl chain and a phospholipid head group.

PEG: Polyethylene glycol, is a highly biocompatible polymer used to increase the water solubility of compounds and reduce non-specific protein adsorption, improving its stability and cycle time in living organisms.

TCO: Trans-cyclooctenyl, is a functional group that is commonly used in other molecules"Click Chemistry"Reactions, such as binding to compounds containing maleamide or other nucleophiles, form stable covalent linkages.

MW:2000 means that the molar mass of this compound is 2000 grams mol.

Therefore, DSPE-PEG-TCO may be used in applications such as drug delivery, molecular labeling, or bioimaging in the biomedical field, often for specific reactions with nucleophile-containing molecules to achieve labeling or modification of specific molecules.

TCO trans-cyclooctene"Yes"trans-cyclooctene", is a cyclic olefin containing eight carbon atoms with a trans-double bond. TCO is commonly used as:"Click Chemistry"A nucleophile in a reaction that reacts with an electrophile (e.g., tetrazine or maleimide) to form a stable cycloaddition product. This reaction is very fast, efficient, and highly specific, so TCO is often used in biomarkers, drug delivery, and other biomedical applications.

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: Qi Yue Hao February 19, 2024.

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