Product name: DSPE-Polysarcosine66 Phosphatidylsinosine.
The polymer PEG derivative DSPE-Polysarcosine66 is a compound composed of:
DSPE: stands for 1,2-distearoyl-sn-glycero-3-phosphatidylcholine (dioleoylphosphatidylcholine). This is a phospholipid molecule commonly used in the construction of nanoparticles or liposomes with a dialkyl chain and a phospholipid head group.
Polysarcosine66: This is a polymer consisting of 66 sarcosine units. Sarcosine is a natural amino acid derivative with good biocompatibility and water solubility.
Therefore, DSPE-Polysarcosine66 may be a material used in the biomedical field with a structure that combines two moieties, phospholipids and polysarcosine. This polymer may have the dual function of being able to interact with lipids to form nanoparticles or liposomes, and to provide the biocompatibility and water solubility of polysarcosine. This material may have potential applications in drug delivery, bioimaging, tissue engineering, and more.
Sarcosine is a natural amino acid derivative, also known as N-methylglycine. It is a colorless and odorless solid with the chemical formula CH3NHCH2COOH.
Sarcosine plays a variety of important biological functions in living organisms, including methylation reactions, neurotransmitter metabolism, and metabolic regulation of muscle tissue. In addition, sarcosine is also used as an intermediate in chemical synthesis for the preparation of various compounds, such as polymers, pharmaceuticals, etc.
In the field of pharmaceutical research, sarcosine and its derivatives have also been studied for psychiatric diseases such as depression and psychosis, as well as for diseases such as cancer and diabetes. In addition, sarcosine is also used as an amino acid derivative in some cosmetics, which has the functions of regulating oil secretion and promoting stratum corneum metabolism.
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: Qi Yue Hao February 19, 2024.