Introduction.
KEAP1 is an important antioxidant protein that regulates intracellular levels of oxidative stress and protects cells from oxidative damage. The keap1 recombinant protein is cloned and expressed by genetic engineering technology, which has a wide range of application prospects. In this article, we will provide a comprehensive introduction to the properties of KEAP1 recombinant protein and its mechanism of action in biological functions.
Catalog No. PA1000-7073
Preparation and characterization of keap1 recombinant protein.
The Keap1 gene was amplified from human cells by PCR technology, and then cloned into an expression vector and expressed in an appropriate host cell to obtain the Keap1 recombinant protein. After purification and identification, the KEAP1 recombinant protein has high purity and activity and can be used for further biological research and applications.
Structure and function of keap1 recombinant protein.
Keap1 is a transmembrane protein containing multiple domains, including several oxidation-sensitive cysteine residues. KEAP1 regulates intracellular antioxidant responses by controlling the stability and activity of NRF2 by interacting with NRF2 protein. KEAP1 recombinant protein can bind to NRF2 to form a complex, promote the degradation of NRF2, and then inhibit the initiation of intracellular antioxidant reactions.
The role of keap1 recombinant protein in biological function.
1.Regulates oxidative stress levels: KEAP1 recombinant protein, as an antioxidant protein, regulates intracellular oxidative stress levels and protects cells from oxidative damage.
2.Cell proliferation and apoptosis: KEAP1 recombinant protein is involved in the regulation of cell proliferation and apoptosis, and plays an important role in cell growth and development.
3.Occurrence and development: Keap1 recombinant protein is closely related to the occurrence and development of tumors, and can be used as a target for research.
4.Drug Research & Development: KEAP1 recombinant protein can be used to screen antioxidants and drugs to develop new drugs with antioxidant activity.
Conclusion. The KEAP1 recombinant protein plays an important role in biological functions by regulating intracellular levels of oxidative stress and protecting cells from oxidative damage. With the deepening of the research on KEAP1 recombinant protein, it is believed that its application prospects in the biomedical field will become more and more broad.
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