This article will focus on hair loss in men and women, and we will delve into the biological basis of hair loss, including how sex hormones and genetic factors contribute to the difference in hair loss between men and women. At the same time, we will ** the role of hair follicle stem cell active factor in this process, emphasizing its importance in gender alopecia. It aims to provide readers with a deeper and more comprehensive understanding of this health challenge.
Male hair loss: Androgenetic alopecia and hereditary alopecia are the two main types of hair loss in men. Androgenetic alopecia, also known as male pattern baldness. This type of hair loss usually occurs gradually in adulthood and is mainly affected by androgens, specifically the male hormone testosterone. Androgenetic alopecia is characterized by a gradual reduction of hair on the forehead and crown of the head, creating a typical "M" shaped hairline.
Elevated levels of testosterone in men, especially when testosterone is converted to dihydrotestosterone, may cause hair follicles to be more sensitive to androgens, which can affect the normal growth cycle of hair.
Hereditary alopecia, also known as premature alopecia, runs in families and usually manifests as severe hair loss at an early stage. Hereditary hair loss may be related to the interaction of multiple genes that may affect the life cycle of hair, making it more susceptible to androgens.
Female hair loss: First of all, a common type of hair loss in women is hereditary alopecia, which is similar to that of men but presents a different pattern. Hereditary hair loss tends to appear in women as a gradual thinning of the crown of the head, but generally does not form the typical "M" shaped hairline. This type of hair loss tends to run in families, and a woman's mother or grandmother may have a hair loss problem that increases a woman's risk of developing hereditary hair loss.
Secondly, hair loss caused by estrogen deficiency is another important type of hair loss in women. When estrogen levels in a woman's body decline, such as during menopause or for other reasons, hair may become more brittle and the growth cycle is shortened, leading to hair loss problems.
In addition to this, female hair loss may also be associated with specific menstrual cycles, such as pregnancy and childbirth. During pregnancy, hormone levels in women can change significantly, which can lead to temporary increased hair loss in some women, and after childbirth, the problem may gradually lessen due to the recovery of hormone levels.
In contrast, the probability of hair loss in men is the probability of hair loss in women.
Androgenic effects: Androgens (testosterone) play a key role in male hair loss. Testosterone levels in men are relatively high, especially after puberty, which makes men more susceptible to androgen-induced hair follicle sensitivity, which contributes to the occurrence of androgenetic alopecia. On the contrary, women have lower levels of androgens in their bodies, so women are relatively less affected by this type of hair loss.
Genetic factors: The genetic mechanism of hair loss is closely related to sex and follows Mendelian laws of inheritance. Gene A stands for no hair loss, and gene A stands for hair loss. For men, hair loss is usually dominantly inherited, that is, only one gene for hair loss needs to be inherited from the mother to show the characteristics of hair loss, resulting in a higher probability of hair loss in men. Female hair loss is recessive, and two hair loss genes need to be inherited from both parents to show the characteristics of hair loss, so the probability of female hair loss is relatively low. This inheritance pattern explains the higher incidence of hair loss in men than in women, and the way genes are transmitted is closely related to physiological differences between sexes.
Effect of hair follicle stem cell activity factor:
In male hair loss, androgens affect the balance of active factors of hair follicle stem cells, resulting in a gradual reduction in hair follicles, a shortened growth cycle, and ultimately a gradual thinning, reduction, and loss of hair. This imbalance may include a decrease in growth factors, an increase in inhibitory factors, etc., which affect the normal function of hair follicles.
In female hair loss, hormone level fluctuations and genetic factors may contribute to different types of hair loss, and the regulation of hair follicle stem cell active factors plays an important role in this. For example, during pregnancy, hormone levels in a woman's body rise, which can lead to temporary hair loss, but this is not a pathological condition. In stages such as menopause, the decline in hormone levels may be related to the deficiency of active factors in hair follicle stem cells, increasing the risk of hair loss in women.
Therefore, an in-depth understanding of the regulatory role of hair follicle stem cell active factors in hair loss and the possible impact of factor imbalance has led to the exploration of how to maintain hair health and improve hair follicle activity.
Behind this scientific exploration, scientists from Guangdong Zhongke Life Stem Cell Laboratory have successfully induced mesenchymal stem cells into hair follicle stem cells and hair follicle precursor cells in vitro through advanced technical means. The extracted active ingredient of hair follicle stem cells, in small molecule form, has excellent permeability and chemotaxis activity. These factors, after being applied to the hair sparse areas, penetrate deeply** to reach the hair follicle layer, initiating and activating the self-repair mechanisms of hair follicle stem cells. This mechanism of action helps to nourish and repair hair follicle tissue, providing an ideal environment for hair to grow.
These active ingredients not only provide support to maintain the structure and function of hair follicles, but also create an ideal environment conducive to healthy hair growth. Therefore, the combination of science and biology provides a new and efficient solution to the problem of hermaphroditism.