6-Chloro-5-nitroquinoline (CAS: 86984-32-9), also known as 6-chloro-5-nitroquinoline, is an important organic compound with the following physical and chemical properties:
6-chloro-5-nitroquinoline is a yellow solid that appears in a crystalline state at room temperature and pressure. Its melting point is about 120-125 °C, and its solubility increases with increasing temperature. At room temperature, it is non-volatile and has good stability.
6-chloro-5-nitroquinoline is a nitrogen-containing heterocyclic compound with certain activity. It can undergo a variety of chemical reactions such as nucleophilic substitution reaction, oxidation reaction, etc. Under alkaline conditions, 6-chloro-5-nitroquinoline can undergo a elimination reaction to form different derivatives.
At present, the synthesis routes of 6-chloro-5-nitroquinoline mainly include chlorination-nitrification and nitrosylation synthesis. Among them, chlorination-nitrification is a more commonly used synthesis method, which is prepared by nitrification reaction of quinoline chloride to obtain the target product.
The methods for preparing 6-chloro-5-nitroquinoline include nitrosylation synthesis method, chlorination-nitrification method, etc. The nitrosylation synthesis method is to prepare the product by reacting the corresponding chloroquinoline with nitric acid; The chlorination-nitrification method is to chlorinate chloroquinoline first and then nitrate to obtain the target product.
As an important organic intermediate, 6-chloro-5-nitroquinoline is widely used in pesticides, pharmaceuticals and other fields. It can be used as a raw material for the synthesis of certain pesticides, and can also be used in the production of antimalarial drugs and other medicines.
Microchannel technology is increasingly widely used in the field of organic synthesis, and it also has potential applications in the synthesis of 6-chloro-5-nitroquinoline. Through the microchannel reactor, the advantages of precise control of reaction conditions and high-efficiency synthesis can be realized, which is expected to promote the production of 6-chloro-5-nitroquinoline in the direction of continuous and efficient development.
In summary, 6-chloro-5-nitroquinoline, as an important organic compound, has abundant physical and chemical properties and is widely used in pesticides, medicine and other fields. In the future, with the continuous development of microchannel technology, it will provide more possibilities for the synthesis of 6-chloro-5-nitroquinoline and promote its application in industrial production.