Nvidia has made extensive use of the 12vhpwr interface on the latest generation of GeForce RTX 40 series graphics cards. However, there have been many reports of 12vHPWR connectors overheating and melting last year, and although it is more to blame on "user misinstallation", it seems to be the consensus that bending the cable can easily cause excessive pressure on the contact points, resulting in a higher potential risk. Subsequently, PCI-SIG prepared a file called "12V-2 6 PCIe 6."0" connector new design, appeared in CEM 51 specification to replace the existing PCIe 50 standard 12vhpwr. 
GeForce RTX 40 Series graphics cards and some new power supplies have already seen this 12V-2 6 power connector available for more stable connectivity and power.
According to TechPowerUp, with the widespread use of 12V-2 6 connectors, it has caused more discussions in the hardware community, and recently some netizens have brought more detailed information, showing that the 12V-2 6 connector has the "H++" symbol on it, which supports up to 675W power output, while the familiar 12Vhpwr connector is the "H+" symbol and supports up to 600W power output. 
It is understood that the 12V-2 6 power supply interface first appeared last year, used for individual GeForce RTX 40 series graphics cards, such as Founders Edition, and a large number of shipments are mainly focused on the GeForce RTX-40 Super card series graphics cards launched this year, but some manufacturers' new products are actually still using the 12VHPWR power supply interface, and there are no unified requirements. It is rumored that AMD is also considering a 12V-2 6 power supply interface, but there is no new development for the time being.
Although it has recently been reported that Nvidia's next-generation GeForce RTX 50 series will replace the new 16pin power supply connector, some industry insiders have come forward to refute the rumors.