XPD (Xeroderma Pigmentosum Complementation Group D) recombinant protein is an important protein that is involved in the regulation of DNA repair and transcription processes, and plays a key role in cell survival and gene stability. In this article, we will provide a comprehensive introduction to the XPD recombinant protein and elucidate its important role in biological function. Catalog No. PA1000-7722
First, let's take a look at the basics of the XPD recombinant protein. XPD protein is a nuclease encoded by the gene XPD and is widely expressed in human cells. It belongs to the DNA-dependent ATPase superfamily and structurally contains the Helicc domain of the N-terminus and the Arch domain of the C-terminus. XPD proteins play a vital role in ribonucleic acid protein synthesis and DNA damage repair.
XPD recombinant proteins are mainly involved in two important biological functions: DNA repair and transcriptional regulation. During DNA repair, XPD proteins work with other nucleases to form nuclease complexes that repair and rebuild damaged DNA. XPD proteins play a particularly important role in the nucleotide exorepair pathway, which is able to identify pathological structures in DNA. In addition, XPD proteins also play an important role in base excision repair and homologous recombination repair.
In addition to its role in DNA repair, XPD proteins are also involved in regulating gene transcription processes. Within the nucleus, XPD proteins bind to other cofactors to form transcriptional complexes that regulate the transcription level of genes by recognizing and binding to the promoter region of DNA. The role of XPD proteins in RNA polymerase complexes is thought to promote the stability and accuracy of RNA synthesis.
Overall, XPD recombinant proteins play an integral role in cell biology functions. It maintains the stability and normal functioning of cellular genes by participating in DNA repair and transcriptional regulation processes. The in-depth study of XPD proteins will help us better understand the biological mechanisms of cells and provide new ideas and methods for related diseases.
In conclusion, XPD recombinant protein is a protein with important biological functions that plays a key role in DNA repair and transcriptional regulation. Through an in-depth understanding of its function, we can better understand the biological regulatory mechanisms within the cell, and provide a reliable basis for the development and application of related research fields.