This article is provided by Shandong Quankeruida Instrument and Equipment.
Eye drop bottle tightness testerIt is a device specially designed to test the sealing performance of eye drop bottles. This article will introduce in detail how eye drop bottle tightness testers work, test methods, and their importance in ophthalmic drug packaging safety to help you better understand and practice this field.
1. Overview of eye drop bottles
The eye drop bottle is a drug dosage form commonly used in ophthalmic diseases**, and the sealing performance of its packaging is of great significance to the effectiveness and safety of the drug. Since the eye drops act directly on the eyes, the requirements for the transparency, air tightness and pressure resistance of the packaging are very strict. Tightness test is an important indicator in the quality inspection of eye drop bottles, which is related to the quality stability of drugs during storage and transportation.
Second, the working principle of the eye drop bottle tightness tester
The eye drop bottle tightness tester mainly uses the vacuum attenuation method for detection. During the test, the eye drop bottle is placed in the test equipment and the corresponding vacuum level and detection time are set. By observing the change of pressure in the bottle, the sealing performance of the bottle body is judged to be up to standard.
3. Test method for the tightness of eye drop bottles
1.Take several test bottles, under the condition of torque 55-80n·cm, the bottle mouth and bottle cap should be properly matched, and no slipping teeth should be allowed.
2.Take several test bottles, open the bottle first, then tighten the cap (use a force wrench to tighten the bottle and the cap with a torque wrench, the torque is 55-80N·cm), place it in the container with an air extraction device, add a baffle, immerse it in water, vacuum it to a vacuum degree of 20kpa, and maintain it for 2 minutes, and there shall be no water or bubbling in the bottle.
4. The importance of eye drop bottle tightness tester in ophthalmic drug packaging safety
1.Ensure the effectiveness and safety of drugs: The eye drop bottle with good sealing performance can effectively prevent the external water vapor, microorganisms and other contamination of the drug, and ensure that the drug maintains a stable efficacy within the validity period.
2.Improve product quality: Through the detection of the tightness of eye drop bottles, the bottles with poor sealing performance can be screened out to ensure the stable quality of the products in the market circulation.
3.Comply with national standards: Sealing performance testing is a necessary part of the quality testing of eye drop bottles, which meets the requirements of relevant regulations and standards for pharmaceutical packaging in China.
4.Reduce drug loss: Eye drop bottles with good sealing performance can reduce the loss of drugs during storage and transportation, saving business costs.
5. Summary
The eye drop bottle tightness tester plays an important role in the safety of ophthalmic drug packaging. By testing the sealing performance of eye drop bottles, the effectiveness and safety of drugs are guaranteed, product quality is improved, national standards are met, and drug loss is reduced. With the continuous growth of the ophthalmic drug market, the importance of eye drop bottle tightness tester in the pharmaceutical industry will become increasingly prominent.