nGRN (neurite growth-promoting protein) is a neuronal protrusion promoting protein, which plays an important role in the development and repair of the nervous system by promoting the growth and regeneration of neurons. nGRN recombinant proteins are artificially synthesized by genetic recombinant technology and have the same biological function, but are more readily available and applied. In this article, we will provide a comprehensive analysis of the basic information and role of the ngrn recombinant protein in biological functions. Cat. No. PA1000-7801
First, basic information about the ngrn recombinant protein. ngrn is a membrane-linked protein with a molecular weight of about 80 kDa and consists of a single-chain polypeptide. It mainly contains a neuronal growth factor domain, which can bind to the surface of neurons and promote the growth and regeneration of neurons. The ngrn recombinant protein is obtained by inserting the ngrn gene into the host cell through genetic engineering, and then using cell expression and purification technology.
In terms of biological function, ngrn recombinant proteins have the following important roles. First, nGRN can promote protrusion growth in neurons. Neurons need to continuously grow new protrusions to form new synaptic connections during development and repair, and NGRN can activate signaling pathways and promote neuronal growth by interacting with the cell surface. Second, nGRN can enhance the sensitivity of neurons to environmental stimuli. NGRN can regulate the permeability and electrical activity of neuronal cell membranes, enhance the excitability of neurons, and make them more susceptible to external stimuli. In addition, nGRN can also promote the regeneration of neuron protrusions. In neurological damage or neurodegenerative diseases, NGRN can promote the regeneration and repair of damaged neurons, speeding up the ** process.
Overall, ngrn recombinant proteins play an important role in the development and repair of the nervous system. By promoting neuron growth and regeneration, enhancing neuronal sensitivity, and promoting neuronal regeneration, NGRN can help promote functional recovery and repair of the nervous system. Therefore, ngrn recombinant protein has a wide range of application prospects, which can be used in neurological diseases, providing a new avenue for neuroscience research and clinical application.
In summary, ngrn recombinant proteins play an indispensable role in biological functions. By promoting the growth and regeneration of neurons, enhancing neuronal sensitivity and promoting neuronal regeneration, NGRN provides important support for the development and repair of the nervous system. It is hoped that through the in-depth research and application of ngrn recombinant protein, it can open up new possibilities for the development of neuroscience and neurological diseases.