Targeting is currently the most widely used tumor method, especially in lung cancer, and has achieved good results. Moreover, there are many targeted ** drugs that can be applied to lung cancer, giving patients a lot of choices.
If you want to apply targeting**, genetic testing is generally required, and the appropriate drug is selected according to the results of genetic testing. For example, if the EGFR gene mutation is detected, drugs such as gefitinib and osimertinib can be given; If the ALK gene is found to be positive, drugs such as ceritinib and alectinib can be given.
However, there are still some patients who have undergone genetic testing and have no corresponding gene mutations and no targeted drugs that can be applied. So how do you go about this type of person? How to adjust Chinese medicine?
1. What are the best methods to use?
1. Can't you use targeting without driver genes? No, there are many targeted drugs, and there is a class of targeted drugs that inhibit neoangiogenesis, which we call "vascular targets", and this kind of targeted drugs do not require driver genes.
We know that the growth of the tumor requires the growth of the blood, and as the tumor grows, there will be new angiogenesis to feed the tumor. Without new angiogenesis, the tumor does not receive adequate nutrition**, and the tumor cannot continue to grow.
Vascular targets have achieved certain clinical results, but the effect is generally better when used together, and less when used alone.
2. In addition to targeting, immunity is also widely used in lung cancer, if you can't do targeting, you can also choose to carry out immune checkpoint detection to see if you can be immune**.
Of course, without a driver gene, there is a good chance that there are no immune checkpoints, and immunity** may not be used.
Clinically, immunology** is usually carried out in conjunction with chemotherapy, and in lung cancer, many people also benefit from immunity**.
3. Traditional methods still account for a large proportion of lung cancer, and most of the patients still need surgery, radiotherapy or chemotherapy, even if they use targeted and immune.
For lung cancer patients without driver genes, the traditional approach is called the primary option.
Surgery, radiotherapy and chemotherapy, as traditional methods, have been used in clinical practice for decades, and have accumulated rich experience, and everyone is familiar with them.
Clinically, an appropriate plan will be formulated according to the stage of the disease, the type of pathology and the patient's constitution.
IIHow should Chinese medicine be adjusted?
For lung cancer patients without driver genes, how should TCM be adjusted? In fact, there is quite a lot of experience in this area, why?
Before the application of targeted ** in clinical practice, we have been using the traditional ** method, and the ** method of combining traditional Chinese medicine with surgery, radiotherapy and chemotherapy has also been used for many years.
After the advent of targeted drugs, there was research on the combination of traditional Chinese medicine and targeted drugs.
So compared with lung cancer with driver genes, what aspects should be paid attention to in lung cancer TCM** without driver genes?
More anti-tumor** is needed
Due to the lack of a ** method, the ** effect on the tumor is not so strong, so when carrying out traditional Chinese medicine, we should pay attention to the overall anti-tumor effect, and take the inhibition of tumor as the first purpose.
In clinical application, it is also necessary to make corresponding adjustments according to the patient's constitution and disease stage. For example, in the early stage, when the physique is better, the anti-tumor effect can be strengthened; In the advanced stage of the disease, when the physique is weak, it is necessary to strengthen the ability to tonify and maintain the patient's physique.
Different
Generally speaking, the *** of chemoradiotherapy is greater than the targeting**, so during the chemoradiotherapy, we should pay attention to the *** of the patient and make targeted adjustments, and even preventive medication. For example, before chemotherapy, we know that chemotherapy has a greater impact on the digestive system, and patients are prone to digestive symptoms, so we can add some spleen and stomach strengthening drugs in advance to enhance the function of the digestive system to alleviate possible digestive symptoms.
** Differences in the way
Targeted** can be given concurrently with chemotherapy, on its own, or orally over a long period of time. However, chemoradiotherapy cannot be done every day, and after the end of chemoradiotherapy, there is a lack of follow-up.
At this time, traditional Chinese medicine can play a better role in sustaining the disease, preventing the prevention and metastasis, and alleviating all kinds of uncomfortable symptoms of patients.
Patients with weak constitution
Some patients are weak or older, and cannot bear the toxicity of radiotherapy and chemotherapy*** After genetic testing, and unable to use targeted drugs, they will fall into a situation where there is no drug available. At this time, in fact, the progression of the tumor can be controlled through traditional Chinese medicine, and the patient's physique can be restored.
IIISome advice for lung cancer patients who cannot apply targeted **
1. Unable to apply targeting** does not mean that it can't**, surgery, radiotherapy and chemotherapy can also achieve good results, so there is no need to be too anxious about this problem.
2. The disease needs to be comprehensively considered according to the disease stage, pathological classification and the patient's physique, not to say "I think this is good to use this", but to take into account the overall state of the patient and consider it for the long term.
3. There is no continuation of targeted drugs, many people will look for some home remedies, earthworks and even health products, it is recommended that you do not apply them at will, and consult a professional doctor.