Knee osteoarthritis is a chronic degenerative bone and joint disease characterized by degeneration, destruction and bone hyperplasia of knee cartilage, which is mainly manifested as joint pain, swelling, deformation and dysfunction. As the saying goes, people grow old first, and with age, the knee joint is caused by cumulative damage, and with the aging of China's population, the incidence of knee osteoarthritis is on the rise.
There are two main factors that cause knee pain, one is inflammatory and the other is mechanical. Inflammatory problems can be alleviated with medications** and mechanical factors can be relieved with knee orthoses.
Squeezable extremity pressure bands to draw effusion** inflammation.
The most typical clinical symptoms of knee arthritis are pain and swelling, and swelling generally represents joint effusion caused by abnormal synovial function of the knee joint, which usually produces more severe pain or discomfort.
When there is a large amount of fluid and tension in the joint, a joint puncture can be performed to completely evacuate the fluid and blood. Therefore, the clinical treatment method for the onset of knee arthritis is generally to eliminate the cause of swelling, extract the fluid in the knee joint, reduce the pressure of the swelling on the knee joint capsule, and then inject analgesic and anti-inflammatory drugs into the joint, and inject joint lubricant after the water accumulation is controlled to replace the function of the extracted joint fluid.
Traditionally, the doctor and one or two assistants squeeze the patient's knee capsule, patella, popliteal fossa, etc. with their bare hands to drain the effusion. This method has the following problems: waste of medical human resources and physical consumption; The manual extrusion efficiency is low and the operation is time-consuming; Unable to accurately control the extrusion pressure, incomplete extrusion; Relying on the operator's experience to judge the pressure in the knee joint, there is no quantitative standard as a reference, and each operation is not replicable.
The team of Academician Dai Yurong and Professor Wang Jinwu of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine has invented a negative pressure controlled squeezable limb pressure band to assist in the extraction of knee joint effusion, which can quantify the pressure exerted on the knee joint, make the negative pressure in the joint cavity more accurate and quantifiable, and the suction effect of the effusion is more stable, which is basically comparable to the arthroscopic joint irrigation effect, and the time is short, basically non-invasive, low cost and reliable effect.
The knee joint is squeezed by the deformation caused by the inflation of the annular balloon, so that the fluid in the joint cavity can quickly gather together.
3D printed knee orthosis solves the problem of alignment.
Skewed alignment of the lower extremities is another cause of knee pain, and the knee space often narrows on one side and the femoral and tibial heads wear and tear increases, resulting in knee pain.
Among the non-pharmacological modalities, the use of knee orthoses in the early and middle stages of knee osteoarthritis is the most important means long before surgery.
The team of Academician Dai Yurong and Professor Wang Jinwu from the Department of Orthopedics of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine proposed an improved single (double) reducer orthopedic principle on the basis of the overall reducible orthopedic principle, and designed a single (bi) reducible knee orthosis. By applying axial tensile force of different magnitudes on both sides of the knee joint, according to the principle of action and reaction force, the principle of lever balance and the principle of force decomposition, a corrective moment in the direction of the side with less force is generated, and the local load is reduced on one side (both sides) while correcting the force line and reducing the load on the affected side of the patient, so as to avoid aggravating the wear and tear of cartilage.
On this basis, the team also applied 3D printing technology to the design and manufacture of knee orthoses, and developed a new type of personalized 3D printing single (double) side reload-reducing knee orthoses, which not only reduced the weight of the orthosis but also greatly improved the comfort of patients wearing the orthosis.
Clinic hours. 
Expert presentation. 
Jinwu Wang, M.D., is the chief physician of the Department of Orthopedics of the Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, a professor at Shanghai Jiao Tong University School of Medicine, and a part-time researcher, doctoral supervisor and postdoctoral supervisor of the School of Biomedical Engineering of Shanghai Jiao Tong University. Chief Scientist of the Ministry of Science and Technology of the 13th and 14th Five-Year Plans, Chief Scientist of the Institute of Translational Medicine of Shanghai Jiao Tong University, and the 5th "Outstanding Achievement" People's Famous Doctor. Director of the National Major Science and Technology Infrastructure (Shanghai) Innovative Medical Device Registration Research and Clinical Transformation Service Center of Translational Medicine, Director of the Digital Medicine and Biological 3D Printing Laboratory, Deputy Director of the Engineering Research Center of the Ministry of Education for the Clinical Transformation of Digital Medicine, Deputy Director of the Key Laboratory of Intelligent Control and Advanced Technology of the Ministry of Civil Affairs, Chairman-elect of the Shanghai Digital Medicine Specialty Branch of the Chinese Medical Association, Vice Chairman of the Digital Orthopedic Trauma and Joint Committee of the Chinese Medical Association, Evaluation expert of the State Food and Drug Administration (NMPA), excellent technical leader of Shanghai, leader of key disciplines of bone and joint medicine of Shanghai Municipal Health Commission, leading clinical talent in Shanghai, chairman of Shanghai Medical Engineering Research Association, vice chairman and secretary general of Shanghai ** Assistive Devices and Geriatric Welfare Industry Technology Innovation Strategic Alliance, vice chairman of the Digital Orthopedics Special Committee of the Medical Engineering Branch of the Chinese Medical Association, vice chairman of the Sports Medicine Professional Committee of the Chinese Research Hospital Association, Vice Chairman of the Biomaterials Advanced Manufacturing Branch of the Chinese Society of Biomaterials, Vice Chairman of the 3D Printing Technology Branch of the China Pharmaceutical Biotechnology Association. He has long been committed to the fields of bone and joint surgery, digital medicine, bone and joint bio3D printing and orthopedics, and his bio3D printing project has been featured in Nature. It has successively undertaken 10 national projects, including the 13th Five-Year Key R&D Plan of the Ministry of Science and Technology (bio-3D printing), the 14th Five-Year Key R&D Plan of the Ministry of Science and Technology (digital medicine and micro and nano biomaterials), and the "863" and "973" sub-projects of the Ministry of Science and Technology. The completed "3D printed lunate" is one of the smallest joints in the human body 3D printing, which has been declared and patented, and has been clinically transformatively applied. He has participated in the compilation of 19 monographs, 12 monographs as editor-in-chief or associate editor-in-chief, 1 chief translator and 1 associate chief translator, and more than 100 articles with high impact factors, including sub-journals of Nature and Science, have been published as the first author or corresponding author. In Shanghai Jiaotong University, a postgraduate course on the cross-transformation of digital medicine and 3D printing was established. Won the first prize of Shanghai Technological Invention Award in 2022 with the first finish, and the project name is "Development of Key Technologies and Equipment for Digital Diagnosis and Treatment of Limb Osteoarthritis". He has won the first prize of science and technology of the Ministry of Education, the first prize of Shanghai Medical Science and Technology, the first prize of Shanghai ** Medical Science and Technology Award, the first prize of Chinese Medical Science and Technology Progress Award, the first prize of Jiangsu Medical Science and Technology Award, and the first prize of Jilin Science and Technology Award.
Under the guidance and support of Academician Dai Yirong, he took the lead in applying for the first 3D printing medical device registration certificate in China, and it was also the first 3D printing medical device registration certificate for the transformation of scientific research enterprises affiliated to Shanghai Jiao Tong University under the registrant system.
Specialty: Minimally invasive complex peri-shoulder fractures**; Minimally invasive rotator cuff injury and shoulder instability under shoulder arthroscopy**; shoulder and elbow replacement; Clinical transformation of 3D printing** assistive devices and 3D printing of intra-bone plants, limb salvage of shoulder joint tumors through microsurgery and customized artificial joint technology**.