This article is from "Nankai Sun Pharmacist", which is used for medical science popularization for reference. Improve memory, delay brain failure, and prevent dementia, these 4 Chinese patent medicines, you must know:
1. Tianzhi particles:
The formula is mainly composed of gastrodia hook vine drink, which comes from the modern medical scientist Hu Guangci's "New Meaning of Miscellaneous Disease Syndrome and Treatment", which is composed of gastrodia, hook vine, stone cassia, eucommia, acacia flower, gardenia, skullcap, chicken blood vine, Sichuan hyssop, motherwort, etc., which has the effects of nourishing the liver and kidney, flattening the liver and latent yang, clearing heat and activating blood, and calming the nerves. Fang Zhong Tianma Ping liver quenching wind, nootropic and calming the nerves; Hook vine clears heat and calms the liver, extinguishes wind and relieves spasms; Stone Cassia Town Liver Latent Yang; Eucommia ulmoides nourishes the liver and kidneys, strengthens muscles and bones; Sophora flowers clear heat and cool blood; Gardenia clears heat and fire, and is good at removing weakness and trouble; Skullcap clears heat and dampness; Shou Wu vine nourishes blood, nourishes the heart and calms the nerves; Sichuan ox knee nourishes the liver and kidneys, strengthens muscles and bones, and leads blood down; Motherwort nourishes blood and invigorates blood, dispels blood stasis and regulates menstruation. The combination of various medicines can play the role of calming the liver and latent yang, and calming the nerves.
Acetylcholine is closely related to learning and memory activities, and a decrease in acetylcholine content in the brain will lead to significant intellectual disability. Animal experiments have shown that Tianzhi granules can promote the activity of basal preacetyltransferase antibody (CHAT) and improve the learning and memory ability of rats with vascular dementia, which may be related to the ability of Tianzhi granules to change the activity of acetylcholine metabolizing enzymes. Clinical trials have shown that Tianzhi granules can reduce the viscosity of whole blood, plasma viscosity and reduction viscosity, and reduce the probability of cerebral infarction. In addition, the P300 potential can reflect the neuroelectrophysiological changes of the brain during cognitive processes, and if the latency of the P300 potential is prolonged and the amplitude is increased, the patient's cognitive function can be reduced. It has been reported in the literature that Tianzhi granules can reduce the latency of P300 and increase the amplitude of P300 to improve the cognitive function of patients.
2. Compound Cistanche nootropic capsules:
It is made of Polygonum multiflori, lotus leaf, Cistanche, Dilong, and drainy reed, which aims to nourish the liver, invigorate blood and dispel turbidity, and strengthen the brain and increase intelligence. Fangzhong made Shou Wu and Cistanche are the king's medicines, which nourish the liver and kidneys and benefit sperm and blood; The lotus leaf has the function of raising the sun, and the medicine is up; The earth dragon clears heat and is cold and descends; Leaking reeds bitter cold, not only clearing heat and detoxifying, but also matching with all temperature tonics, so that the whole side is warm but not hot, tonic but not harsh.
Modern pharmacological studies have shown that the preparation of Polygonum multiflorum can reduce blood lipids, anti-atherosclerosis, and anti-aging. Cistanche has a good antioxidant effect. The active ingredient in lotus leaves can reduce blood lipids. Drain also has anti-atherosclerotic effects, and can also reduce the content of lipid peroxide in the serum and reduce cell death. Dilong is widely used in cerebrovascular diseases, and its active ingredient vermikinase can reduce the adhesion rate of platelets and dissolve blood clots in the body. Studies have confirmed that Cistanche nootropic capsule can resist free radical damage, inhibit the release of excitatory amino acids, promote the production of brain-derived neurotrophic factors, increase the deformability of red blood cells, and reduce platelet aggregation. Its alanine-rich myristoylated protein kinase C, an important protein that connects extracellular signaling and neuronal plasticity, is an important protein that connects extracellular signaling and neuronal plasticity, and its dysregulated expression can lead to deficits in learning and memory function. Cistanche Nootropic Capsule can adjust the expression of the action substrate of myristoylated protein kinase C of alanine, thereby improving the cognitive function of patients.
3. Ginkgo biloba leaves:
It mainly contains ginkgo biloba compounds and terpene lactones, mainly ginkgo biloba diflavonoids, isoginkgo biflavonoids, 7-desmethylginkgo biflavonoids (pinklexanthin), ginkgolides, etc. In addition, it also contains a small amount of alkaloids and trace elements and other components. Ginkgo biloba has a variety of clinical effects such as dilating blood vessels, reducing blood pressure, resisting cardiac and cerebrovascular ischemia and reperfusion injury, inhibiting platelet aggregation, anti-thrombosis, lowering blood lipids, anti-atherosclerosis, and improving learning and memory.
Clinical studies have confirmed that Ginkgo biloba can improve the cognitive function of patients with cognitive dysfunction in the elderly and young, and can be used as an effective drug for initial intervention, and its mechanism may be related to the following factors: increasing the M choline receptors in the center, especially in the hippocampus, is conducive to the recovery of memory function due to cerebral ischemic injury, and is also conducive to the improvement of memory function in patients with senile dementia and senile memory loss; Accelerate the conduction of nerve impulses and facilitate synaptic transmission, which is conducive to information acquisition, memory consolidation and reproduction, suggesting that it can improve the learning and memory impairment of patients with dementia. Antagonizes amyloid that causes neuronal necrosis, alleviates the neurotoxicity of amyloid and neurodegeneration caused by free radical damage, and inhibits apoptosis.
4. Huatuo reconstituted pills:
It is a national secret prescription product, which is composed of more than a dozen botanicals such as Chuanxiong, angelica, borneol, etc., which has the function of activating blood and removing blood stasis, dissolving phlegm and channeling, and plays a very good role in the dementia caused by blood stasis and phlegm dampness. Studies have shown that Huatuo re-construction pills ** vascular dementia can improve the intelligence level of patients, improve cognitive function and memory impairment, which is conducive to the improvement and recovery of social activities and self-care ability, and delay the development of the disease. Huatuo reconstituted pills can reduce whole blood viscosity, red blood cell aggregation index, improve red blood cell compliance, and reduce fibrinogen levels. One of the pathogenesis principles of vascular dementia is the existence of hypercoagulability, so Huatuo re-construction pills to improve blood hypercoagulability is conducive to the prevention and treatment of vascular dementia.
In addition, Huatuo reconstituted pills can also reduce the levels of total cholesterol (TC) and triglycerides (TG), and increase the level of high-density lipoprotein cholesterol (HDL-C), so it can improve the clinical symptoms and delay the development of vascular dementia patients by adjusting lipid metabolism. Huatuo rebuilding pills can also reduce cerebral vascular reperfusion damage by increasing the levels of prostaglandin I2 (PGI2) and nitric oxide (NO), and reducing the levels of (thromboxane B2) TXB2 and endothelin (ET), so as to improve cerebral blood flow and enhance learning and memory function.