4-Iodo-2-nitropyridine (CAS: 1003711-88-3) is an organic compound with the following physical and chemical properties:
4-Iodo-2-nitropyridine is a yellow solid with a peculiar odor. Its molecular weight is 20499 g mol, melting point 78-80 °C, boiling point 298-300 °C. At room temperature, it is insoluble in water but can be dissolved in organic solvents.
4-Iodo-2-nitropyridine is an aromatic compound containing iodine and nitro. It can be used as an important intermediate and has a wide range of applications in organic synthesis. It can undergo a variety of chemical reactions such as electrophilic substitution reaction, reduction reaction, etc., and has strong activity.
There are several methods for the synthesis of 4-iodo-2-nitropyridine, and common methods include nitrosylation and iodination reactions. The nitylation reaction is to nitrate 2-nitropyridine through a nitrolating agent to obtain the target product. The iodination reaction is to iodine 2-iodopyridine through an iodination reagent to obtain 4-iodo-2-nitropyridine.
The preparation method of 4-iodo-2-nitropyridine usually needs to be carried out under the condition of stirring, and the control of reaction temperature and reaction time has a great impact on the yield. Reaction conditions often need to be optimized to improve the purity and yield of the product.
As an important intermediate in organic synthesis, 4-iodo-2-nitropyridine has a wide range of applications in pharmaceuticals, pesticides, dyes and other fields. It can be used in the synthesis of pyridine compounds, which has important research and application value.
Microchannel continuity is one of the research hotspots in recent years, which can realize the automation and continuity of the chemical synthesis process. In the synthesis of 4-iodo-2-nitropyridine, microchannel technology can increase the reaction speed, reduce waste generation, and reduce the need for reaction conditions.
With the continuous development of microchannel technology, the application prospect in organic synthesis is broad in the future. Microchannel continuity can improve reaction efficiency, reduce energy consumption, and reduce costs, which is of great significance for the synthesis of 4-iodo-2-nitropyridine.
In summary, 4-iodo-2-nitropyridine, as an important intermediate in organic synthesis, has important application value in the field of chemistry. The development of microchannel continuous technology will provide more possibilities for its synthesis, and it is expected to make greater breakthroughs in this field in the future. Therefore, it is of great significance for the research and development of 4-iodo-2-nitropyridine, which is worthy of further in-depth research and research.