Infection risk and prevention and control in patients with agranulocytosis

Mondo Health Updated on 2024-03-03

Agranulocytosis is a rare but dangerous immune system disorder in which patients are susceptible to various infections due to the extremely low number of neutrophils. With a neutrophil count (ANC) below 1500 L, the risk of opportunistic infections** increases significantly, and when neutrophils fall to severe levels (<500 L), we call them agranulocytosis, and patients are more likely to develop severe infections with serious consequences.

People with agranulocytosis have a weak immune system and few neutrophils in their peripheral blood, making them highly susceptible to a wide range of pathogens. Even ordinary bacteria, fungi, or viruses can pose a huge threat to patients, so people with agranulocytosis need to be extra careful in their daily lives and avoid touching environments or objects that can lead to infection.

In addition to avoiding the source of infection, patients with agranulocytosis also need regular medical check-ups, timely monitoring of neutrophil counts, and appropriate precautions according to the doctor's recommendations**. In the event of an infection, the patient may need to receive a special anti-infection** and may even need to be hospitalized** for safety. In addition, people with agranulocytosis need to follow these tips to reduce their risk of infection:

1.Maintain good personal hygiene, including washing hands frequently, coughing frequently, keeping the environment clean and avoiding contact with potentially contaminated water or food.

2.Avoid crowds and people with contagious diseases, especially during flu season or during outbreaks.

3.Avoid contact with animals and animal waste to prevent the spread of animal-derived infections.

4.Get regular vaccinations, including pneumococcal, flu, and other vaccines that are appropriate for your patient, to boost your immune system's resistance to specific pathogens.

5.Follow your doctor's advice and have regular blood tests and evaluations to detect and manage any signs of potential infection.

Although people with agranulocytosis face the challenge of an increased risk of infection, with proactive** and preventive measures, they can effectively reduce the risk of infection and maintain health. Regular communication with your medical professional, following your doctor's instructions and taking the necessary precautions are key. At the same time, it is also important to maintain good hygiene in daily life, stay away from environments that may lead to infection, and work together to protect your health.

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