CRAT recombinant carnitine acetyltransferase CRAT

Mondo Science Updated on 2024-03-07

CRAT is an enzyme that catalyzes reactions and is mainly involved in amino acid metabolism and important functions in the energy** process. CRAT protein is widely found in eukaryotes and prokaryotes, and its basic information and functional structure are of great significance for studying the body's metabolism and diseases.

Catalog No. PA1000-9419

CRAT is an abbreviation for Carnitine Acetyltransferase, and its basic information is as follows: the molecular weight is about 45 kDa, it is composed of 322 amino acid residues, and is mainly found on the inner mitochondrial membrane. The main function of CRAT is to catalyze the reaction to convert glycine and pyruvate into glycyl methyl and dioxoglycine, while glycyl methyl is involved in the oxidation process of fatty acids and provides important substances for cellular energy**.

The structure of CRAT protein also plays an important role in its function. CRAT is a helix-rich protein with obvious free-moving ability and transfer-acyl activity. Its active site contains essential amino acid residues, which undergo an esterification reaction after binding to the substrate. In addition, the structure of CRAT proteins contains domains that protect substrate binding, ensuring that substrates are properly handled.

CRAT has a wide range of applications in the research field. First, CRAT, as a key catalytic enzyme for amino acid metabolism, plays an important role in the occurrence and development of diseases. For example, patients often have a lipid metabolism disorder, and abnormal CRAT function can lead to obstruction of fatty acid metabolism, which can affect the body's energy** and health. Therefore, by studying the structure and function of CRAT protein, it can provide an important basis for the diagnosis and development of diseases.

Secondly, CRAT is also widely used in drug discovery and biotechnology. Through the study of CRAT, it is possible to design more effective drug targets and develop ** drugs for metabolic diseases. At the same time, CRAT also plays an important role in the field of biotechnology as an important catalytic enzyme, for example in the production of compounds such as acetylglucan and amino acids.

In conclusion, CRAT, as an important catalytic enzyme, plays an important role in amino acid metabolism and energy** processes. Its basic information and functional structure are of great significance for the study of human metabolism and diseases, and provide an important basis for drug discovery and biotechnology. Through continuous in-depth research on the structure and function of CRAT, it will provide more possibilities for disease prevention and development, and promote the development of medicine and life sciences.

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