DSPE PEG DBCO PHOSPHOLIPIDS POLYETHYLENE GLYCOL CLICK CHEMISTRY

Mondo Health Updated on 2024-01-28

Product name: Phospholipid-polyethylene glycol-Click Chemistry.

Product Name: dspe-peg-dbco

Molecular weight: 1k, 2k, 34K, 5K, 10K, 20K (can be customized on demand).

Precautions: Be sure to dry when taking and avoid frequent dissolution and freeze-drying.

Solubility: Soluble in most organic solvents, such as: DCM, DMF, DMSO, THF, etc. It has good solubility in water.

Uses: Only for scientific research, not for human body.

DSPE-PEG-DBCO is a compound obtained by copolymerizing DSPE with PEG and introducing a DBCO functional group at the end of the PEG chain. DSPE-PEG-DBCO has a hydrophobic phosphatidyl group and a hydrophilic PEG chain that forms a stable micelle structure in the aqueous phase. This micelle structure makes DSPE-PEG-DBCO an excellent drug carrier that can encapsulate the drug in the aqueous phase to form stable drug micelles. This drug micelle can effectively increase the solubility of the drug, improve the bioavailability of the drug, and reduce the toxicity of the drug***

In addition to this, DSPE-PEG-DBCO also has high stability, which can maintain the activity of the drug in the body and reduce the degradation and metabolism of the drug. At the same time, DBCO functional groups can also carry out click chemical reactions with azide-containing compounds in organisms to achieve targeted release of drugs in vivo.

Therefore, DSPE-PEG-DBCO has a wide range of applications in drug delivery systems and biomedical engineering. At the same time, DSPE-PEG-DBCO can also be used to prepare nanomedicines, genes, targeting and other fields, providing new ideas and methods for the development of biomedical engineering and drug delivery systems.

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