Uncle Xu is 53 years old this year and was just diagnosed with hyperlipidemia a few months ago, so the doctor prescribed atorvastatin calcium tablets to Uncle Xu. The doctor told Uncle Xu to take medicine on time after he went back, pay attention to his diet, and come back for a follow-up examination in a month.
In the next month, Uncle Xu took medicine on time every day, and strictly controlled his diet, trying to avoid high-fat and high-fat foods. A month later, Uncle Xu went for a follow-up examination with confidence, and after the doctor examined Uncle Xu, he found that Uncle Xu's blood lipids were well controlled, and praised Uncle Xu a few words, asking Uncle Xu to continue to maintain this standard and come back for a re-examination next month.
After going back, Uncle Xu still took medicine on time and ate a balanced diet according to the standards of last month. But after a month,Uncle Xu began to have ** yellowing and yellowing of the whites of his eyes。Uncle Xu thought that he didn't sleep well during this time, so he didn't take it to heart, just during this time, Uncle Xu's daughter got married, and she was very busy inside and out, so Uncle Xu forgot the time for the review, and when he recalled that he wanted to go for the review, it had been half a month. So Uncle Xu thought, then let's just go and check it up next month.
Another month passed,Uncle Xu's yellowing condition still did not improve, and even Uncle Xu began to have symptoms of pain in his right upper abdomenThis time, Uncle Xu finally sensed that something was wrong, and hurriedly made an appointment for the next day's outpatient clinic and went to the hospital to consult a doctor.
After seeing Uncle Xu, the doctor asked him why he had come for a follow-up examination after a few monthsUncle Xu said that he was too busy during this time, so he did not come for a review. A few months ago, I began to have ** yellowing and yellowing of the whites of my eyes, I thought it was caused by not resting well, but I didn't expect it to be getting worse and worse now, and I have been having unexplained pain in my upper right abdomen recently.
When the doctor heard this, he felt that there was something wrong with Uncle Xu's liver, so he asked Uncle Xu to go for a liver function test, and after the test results came outIt was found that Uncle Xu's aminotransferases were more than 3 times higher than the normal value, and it was indeed a damage to liver function！Uncle Xu couldn't believe it for a while, saying that he hadn't drunk or stayed up late during this time, why did he have liver function problems?
The doctor said that Uncle Xu was suffering from liver damage caused by taking atorvastatin calcium tablets。When there is a yellowing of ** and yellowing of the whites of the eyes, Uncle Xu's liver function has begun to be abnormal, and if you come for a re-examination at that time, you can still find it in time, but now, you can only temporarily reduce the dosage of atorvastatin calcium tablets first, and then increase the dosage as appropriate after the liver function returns to normal. If the liver function does not return to normal, then the dressing must be changed.
Uncle Xu regretted it, but he didn't expect it to be a big mistake in a moment. The doctor comforted Uncle Xu, as long as he cooperated well, there would be no problem. In fact, in addition to Uncle Xu, many people will have various problems when taking atorvastatin calcium tablets, so today, we mainly want to learn about atorvastatin calcium tablets.
Atorvastatin calcium tablets are mainly a lipid-lowering drug currently used in clinical practice for hyperlipidemia, which can effectively improve the increase in apolipoprotein B and triglyceride content, inhibit cholesterol synthesis, thereby reducing blood lipids and maintaining blood lipid balance. In addition to hyperlipidemia, atorvastatin calcium tablets can also help hypercholesterolemia, mixed hyperlipidemia, coronary heart disease, atherosclerosis and other diseases, and can also reduce the risk of myocardial infarction and stroke in patients, which is widely used in clinical practice. Moreover, compared with other lipid-lowering drugs, atorvastatin calcium tablets also have great advantages.
Atorvastatin calcium tablets have a good lipid-lowering effect。Atorvastatin calcium can help inhibit cholesterol synthesis, prevent myocardial infarction and stroke, and has a good lipid-lowering effect. In fact, we can see this from Uncle Xu, Uncle Xu only took atorvastatin calcium for one month and his blood lipids dropped, which can also show how good the lipid-lowering effect of atorvastatin calcium is.
Atorvastatin calcium has a rapid onset of action。After some lipid-lowering drugs enter the human body, it takes a certain amount of time to exert their effects, but atorvastatin calcium is different, after atorvastatin calcium enters the human body, it can be quickly absorbed and released by the human body, and can inhibit cholesterol synthesis in the patient's body in a short time, thereby reducing blood lipids.
Atorvastatin calcium has few adverse effects。Any drug will have adverse reactions, but compared with other drugs, the adverse reactions of atorvastatin calcium will be relatively small, the more common ones are muscle pain and muscle weakness, but the probability of this occurrence is also very small, only 1Around 5% to 3%. In addition to muscle pain, there are myositis, rhabdomyolysis, elevated aminotransferases, etc., but the probability of these adverse reactions is smaller, and the incidence is very low.
Atorvastatin calcium is easy to use。Some lipid-lowering drugs will have several dosage forms, but atorvastatin calcium is only available in tablets, divided into three doses: 10mg, 20mg, and 40mg, and in general, the starting dose for adults is 10-20mg, and no more than 80mg per day. Children aged 10 to 17 years should start at a dose of 10 mg and should not exceed 20 mg per day.
Atorvastatin calcium has a long half-life。After taking atorvastatin calcium, the onset time of action is very fast, about 1-2 hours the blood concentration can reach the peak, the half-life is 20-30 hours, the effect time is very long, even if the drug is stopped, the effect time can be maintained for several days.
Atorvastatin calcium tablets mainly act on the liver, and have a very significant effect on the disease of hyperlipidemia, and atorvastatin calcium also has many advantages such as small adverse reactions, fast onset of action, and long half-lifeTherefore, many doctors and patients like to take atorvastatin calcium tablets for high blood pressure. However, although atorvastatin calcium tablets are good, we cannot ignore the following 5 contraindications!
1) Patients with hepatic insufficiency cannot take atorvastatin calcium
Atorvastatin calcium mainly acts on the liver, so if there are patients with liver insufficiency, they should not take atorvastatin calcium, otherwise it may aggravate the condition and make the liver damage more serious. The adverse reactions of atorvastatin calcium also include liver damage, so patients must check their liver function regularly when taking atorvastatin calcium, so as not to be like Uncle Xu, who almost caused a catastrophe.
2) Pregnant and lactating women should not take atorvastatin calcium
When a woman is pregnant, cholesterol and triglycerides are elevated, but both of these components are essential nutrients for fetal development, so women who are pregnant and breastfeeding should not take atorvastatin calcium. In addition, atorvastatin calcium may also affect the fetus and cause fetal malformations, so it is not recommended for pregnant and lactating women.
3) During taking atorvastatin calcium, it is necessary to pay attention to its interaction with other drugs
Atorvastatin calcium should not be taken while taking drugs such as cyclosporine, gefibrozil, clarithromycin, and certain anti-HIV drugs, as this will increase the risk of myopathy and rhabdomyolysis. There are also certain anti-hepatitis C drugs, colchicine, erythromycin, etc., which should also pay attention to the interaction with atorvastatin calcium to avoid adverse effects on the patient's body.
4) Do not drink grapefruit juice while taking atorvastatin calcium
This is because, when a patient ingests a large amount of grapefruit juice (more than 12L), it will reduce the metabolism of atorvastatin calcium, resulting in an increase in blood concentration, which is not good for the liver, and may damage the liver in the long run. Therefore, doctors recommend that grapefruit juice intake should be avoided while taking atorvastatin.
5) Patients with hyperglycemia are better not to take atorvastatin calcium
Because atorvastatin calcium enters the human body, it may cause abnormal blood sugar, and may even cause diabetes, if you already have high blood sugar, then it may lead to diabetes complications, so doctors recommend that patients with high blood sugar should not take atorvastatin calcium. For patients who do not suffer from hyperglycemia, it is also necessary to check blood sugar regularly while taking atorvastatin calcium, and once a problem with blood sugar is found, it is necessary to take medication under the guidance of a doctor.
Atorvastatin calcium has a good lipid-lowering effect, but in the process of taking it, patients must not forget the above 5 contraindications. So, what can we do to avoid contraindications in the process of taking atorvastatin calcium?
Pay attention to your diet and reduce the intake of high-calorie and high-cholesterol foods。The main effect of atorvastatin calcium is to lower blood lipids, if we rely on drugs alone to lower blood lipids, but do not pay attention to the diet at all, it is useless. We must take medicine and diet, so as to better lower blood lipids. Therefore, during the period of taking atorvastatin calcium, it is necessary to consume less high-calorie and high-cholesterol foods, eat lightly, and have a balanced nutrition.
During the course of taking the medicine, you should pay close attention to your body。Although the adverse effects of atorvastatin calcium are relatively small, it cannot be 100% guaranteed that there is no one, so you must observe your body well and seek medical attention in time when you find that something is wrong with your body.
During the course of taking the drug, it is necessary to pay attention to monitoring。It is necessary to monitor the value of blood lipids, liver function and blood sugar, and if the value is found to be high, there is liver function damage, or diabetes, then the drug should be stopped in time. You must not be like Uncle Xu, who only checks once every few months, you must follow the doctor's instructions carefully, and check when the doctor tells you to.
In the process of taking the drug** When there is serious muscle injury, allergies, and liver function damage, the drug should be stopped in time, otherwise it may be life-threatening.
Of course, in the process of taking medicine, you should also pay attention to exercising, and you can try to choose to do more exercises that suit you. At the same time, maintain a good life Xi, be less angry, and maintain a good attitude, which is beneficial to **.
The lipid-lowering effect of atorvastatin calcium is very good, but in the process of taking it, you should also pay attention to the above contraindications, if you have an adverse reaction like Uncle Xu, you should seek medical attention in time and seek help from a doctor.
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3] Liang Decui. "Atorvastatin calcium tablets for coronary heart disease complicated with hyperlipidemia lipid effect were observed. "Everybody's Health Issue 000003(2015):414-415.