National Safe Drug Month Familiar with two brothers, aspirin and amoxicillin

Mondo Health Updated on 2024-01-29

Aspirin and amoxicillin are both "surnamed" Ah, and they both have the word Lin in their names, which look like brothers. But in fact, these two drugs are completely different categories: aspirin is an antipyretic, analgesic, anti-inflammatory drug and antiplatelet drug, while amoxicillin is an antibacterial drug, which can cause serious adverse consequences if taken by mistake. Below, let's take you to see the difference between this pair of "two brothers with familiar faces".

Aspirin. Aspirin has a long history of application, it has antipyretic, analgesic, anti-inflammatory, anti-rheumatic and other pharmacological effects, can be used for fever, toothache, headache, joint pain and rheumatoid arthritis, etc., small doses can also be used in clinical antiplatelets, to prevent transient ischemic attack, myocardial infarction, atrial fibrillation, artificial heart valves, arteriovenous fistula or other thrombosis after surgery. When used for antipyretic analgesia, 03~0.6 grams, 3 times a day, 1 time a day for 4 hours if necessary. When used for antiplatelet use, the usual dose is 75 100 mg once a day.

It should be noted that about 02% of patients who take aspirin may have allergic reactions such as asthma, urticaria, angioedema or shock, and most of them are susceptible. Some of these patients develop breathing difficulties quickly after taking the drug, which can be fatal in severe cases, a phenomenon known as aspirin asthma. Aspirin enteric-coated tablets are easy to disintegrate in the alkaline environment of the small intestine, but not easy to disintegrate in the strong acidic environment of the stomach, so they should be taken on an empty stomach before meals. If taken after a meal, the drug may disintegrate in the stomach due to an increase in the pH of the stomach, which may increase the risk of stomach ulcers and bleeding.

Amoxicillin. Amoxicillin is a commonly used penicillin broad-spectrum antibiotic for diseases caused by sensitive bacterial infections, such as respiratory tract infections, genitourinary tract infections, soft tissue infections, etc., and can also be used for typhoid fever, typhoid carriers and leptospirosis. In addition, amoxicillin can also be used in triple combination with clarithromycin, lansoprazole and other drugs to reduce the rate of peptic ulcers in the stomach and duodenum Helicobacter pylori infection. Its dosage is: for general infection, ** 05 g every 6 8 hours 1 time in a daily dose of not more than 4 g. The daily dose for children is 20 40 mg kg body weight, divided into 2 to 3 doses. For Helicobacter pylori infection, 1 gram each time, once every 12 hours, it needs to be combined with other drugs.

It should be noted that amoxicillin is a penicillin antimicrobial drug, which may cause severe allergic reactions, and it is necessary to determine whether it is allergic before taking it;People who are allergic to penicillin should not take it. It is not suitable for viral infectious diseases, such as the common cold, and is not recommended if there is no co-infection with bacteria. Since the drug is a time-dependent antimicrobial drug, attention should be paid to evenly spaced administration and full course of medication. It is metabolized by the kidneys, so the dose and interval of administration in patients with renal insufficiency need to be adjusted. In addition, antimicrobials such as amoxicillin need to be used under the guidance of a doctor or pharmacist to avoid drug abuse and adverse reactions.

Aspirin and amoxicillin have similar names, but they work completely differently. If amoxicillin is misused as aspirin, it is easy to increase the risk of mucosal ulceration and bleeding, especially in children, and the risk of allergic reaction (Ruiyi syndrome) is likely to increaseMisuse of aspirin as amoxicillin increases the risk of antimicrobial resistance and other adverse effects. Therefore, be sure to carefully check the name of the drug and the package insert when using it, and consult a doctor or pharmacist if necessary.

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