The basic properties of triphenylphosphine are as follows:
Common name: triphenylphosphine.
English name: triphenylphosphine
CAS Number: 603-35-0
Molecular weight: 262285
Chemical formula: (C6H5)3P
Molar mass: approx. 2623 grams of moles.
Appearance: Typically white to light yellow crystalline solid.
Solubility: Soluble in a variety of organic solvents such as ether, dimethyl sulfoxide and benzene, but insoluble in water.
Melting Point: about 80-81°C
Boiling Point: about 377°C
Storage conditions: It should be stored in a dry, cool place, away from fire and oxidants.
These basic properties provide an important reference for the physical properties of triphenylphosphine, which has a wide range of applications in organic synthesis and coordination chemistry.
Triphenylphosphine has a wide range of applications, and the main uses include:
1.Organic synthesis: As an important reagent, triphenylphosphine is widely used in the field of organic synthesis. It can be involved as a nucleophile in catalytic reduction, nucleophilic substitution, and many other reactions.
2.Organometallic chemistry: Triphenylphosphine is often used as a ligand for organometallic compounds to form stable complexes, such as those formed with transition metals, which have important applications in catalysts and organic synthesis.
3.Ligand chemistry: As a type of phosphorus ligand, triphenylphosphine is widely used in coordination chemistry and transition metal-catalyzed reactions.
4.Drug Synthesis: Triphenylphosphine is also used in the pharmaceutical field for the synthesis of certain drugs.
5.Materials Science: In some areas of polymer chemistry and materials science, triphenylphosphine has also shown some potential for applications.
In general, triphenylphosphine plays an important role in organic synthesis, organometallic chemistry, catalysts, etc., and also has related applications in the fields of medicine and materials.
As an important organophosphorus compound, the upstream and downstream products of triphenylphosphine are as follows:
Upstream Products:**
1.Bromobenzene: Bromobenzene is one of the common raw materials used in the synthesis of triphenylphosphine.
2.Phosphorus (III) oxides: Phosphorus (III) oxides are commonly used in synthesis reactions to prepare triphenylphosphine.
Downstream Products:**
1.Organometallic compounds: Triphenylphosphine can be used as an important ligand in organometallic chemical reactions to generate various organometallic compounds.
2.Organic synthesis reaction: Triphenylphosphine is used as a reagent and catalyst in the field of organic synthesis, which can be used to prepare a variety of organic compounds, such as drugs, pesticides, etc.
3.Coordination chemistry: Triphenylphosphine can be used as a ligand in coordination chemistry and transition metal-catalyzed reactions.
These upstream and downstream products form the chain of chemicals associated with the production and application of triphenylphosphine.
The synthesis of triphenylphosphine can usually be carried out by the following routes:
1.Synthesis from phosphorus(III) oxides:
First, phosphorus(III) oxide is reacted with bromobenzene under alkaline conditions to generate triphenylphosphine and sodium bromide.
The reaction equation is as follows:
p_4o_6 + 6c_6h_5br + 6naoh ightarrow 2p(c_6h_5)_3 + 6nabr + 3h_2o \]
2.*Other methods:**
In addition to synthesis from phosphorus(III) oxides, there are some other synthetic routes, such as preparation from triphenylphosphine chloride and sodium amalgamation reactions.
These synthetic routes are common methods used for the synthesis of triphenylphosphine. After the appropriate purification and separation steps, a pure triphenylphosphine product is obtained.
Triphenylphosphine requires special care during transportation and storage as it is somewhat toxic and flammable. Here are some recommended shipping and storage considerations:
Shipping:**1Triphenylphosphine should be shipped in an airtight, fireproof container.
2.Transport vehicles should be equipped with corresponding safety facilities to prevent accidental leakage or other accidents.
Storage: **1Triphenylphosphine should be stored in a dry, cool, well-ventilated place, away from fire and heat sources.
2.Triphenylphosphine should be stored separately from the oxidizing agent to avoid chemical reactions.
In all cases, triphenylphosphine should be handled and stored in strict accordance with relevant regulations and safe operating procedures to ensure safe transport and storage, and appropriate measures should be taken to avoid hazards to the environment and personnel.
The following precautions need to be followed when using triphenylphosphine:
1.Personal Protective Equipment: When handling triphenylphosphine, appropriate chemical protective eyewear, respirators, gloves, and a lab coat should be worn to protect **, respiratory tract, and eyes from contact.
2.Good ventilation: Places where triphenylphosphine is used should have good ventilation to ensure that gas concentrations in the operating area remain at safe levels.
3.Avoid inhalation or contact: Avoid inhaling the gas of triphenylphosphine or prolonging contact with its solid form. Avoid ingestion and never put your fingers in your mouth.
4.First aid measures: In case of accidental exposure to triphenylphosphine, rinse the affected area immediately with plenty of water and seek medical attention.
5.Safe storage: Containers for storing triphenylphosphine should be stored tightly sealed and clearly marked, away from heat and fire.
6.Disposal of waste: Waste triphenylphosphine or items that have come into contact with it should be disposed of in accordance with relevant regulations and standards.
In all cases, triphenylphosphine should be handled and used in accordance with relevant regulations and safe operating procedures to ensure the safety of oneself and others.