Phosphorus tribromoide (PBR3) is an inorganic compound with the following basic properties:
Common name: phosphorus tribromooxychloride.
English name: phosphoryl bromide
CAS Number: 7789-59-5
Molecular weight: 286685
Chemical Formula: PBR3
Molar mass: Approximately 2707 g moles.
Appearance: PBR3 appears as a colorless to pale yellow liquid.
Solubility: Soluble in non-polar solvents such as benzene and tetrahydrofuran, but insoluble in water.
Uses: It can be used as a reagent to convert hydroxyl groups to halogenated groups in organic synthesis, and can also be used to prepare other organophosphorus compounds.
Safety Precautions: PBR3 can cause burns after contact** and eyes and needs to be handled with care.
The main uses of phosphorus tribromide (PBR3) include:
1.Organic synthesis: PBR3 is often used as a reagent to convert hydroxyl groups to halogenated groups, which is of great significance in organic synthesis. It can convert the hydroxyl group in alcohol, phenol and other compounds into halogenated groups for further organic synthesis reactions.
2.Preparation of other organophosphate compounds: PBR3 can also be used to prepare other organophosphorus compounds, such as sulfonamides and phosphoramides, which have important applications in medicine and agriculture.
Therefore, PBR3 has an important use in the field of organic synthesis, can be used to synthesize various organic compounds, and plays an important role in the fields of medicine and agriculture.
As an important chemical agent, phosphorus tribromide (PBR3) involves a series of upstream and downstream products in the production process. Here are some of the possible upstream and downstream products related to PBR3:
Upstream Products:**
1.Triethyl phosphate: one of the raw materials used for the synthesis of PBR3.
2.Bromine: as one of the raw materials for the preparation of PBR3.
3.Purified phosphorus: can also be used to prepare PBR3
Downstream Products:**
1.Halogenated hydrocarbons: obtained by converting hydroxyl groups into halogenated groups by PBR3, such as haloalkanes, halogenated alcohols, etc.
2.Organophosphorus compounds: PBR3 can be used to synthesize various organophosphorus compounds, such as sulfonamides and phosphamides.
3.Pharmaceutical intermediates: Some compounds synthesized using PBR3 in organic synthesis may be used as pharmaceutical intermediates for further use in the preparation of drugs.
These upstream and downstream products form the chain of chemicals associated with the production and application of PBR3.
The synthesis route of phosphorus tribromooxymide (PBR3) usually involves the following steps:
1.*Preparation of phosphorus bromide (PBR5) :* reaction of purified phosphorus with bromine to produce phosphorus bromide. This step is usually performed in an inert atmosphere.
2.Reduction of PBR5 to PBR3: Phosphorus bromide undergoes a reduction reaction, e.g. heating in the presence of a carbon bubbling agent, to give phosphorus tribromide (PBR3).
The specific conditions and methods of operation of synthetic routes may vary depending on the scale of production, safety considerations, and other factors. This synthesis method is one of the more common routes in industry and is used for large-scale production of phosphorus tribromooxychloride.
Phosphorus tribromochloride (PBR3) requires special care during transport and storage as it is dangerous. Here are some suggestions:
Shipping:**1Packaging: PBR3 should be shipped in an airtight container to avoid leakage.
2.*Identification: The transport container should be clearly marked with its chemical properties, hazards and necessary safety warnings.
Storage: **1Environment: PBR3 should be stored in a dry, well-ventilated place, away from fire and high temperatures.
2.*Sealed: Storage containers should be kept tightly sealed to prevent air and moisture from entering.
3.Isolation: PBR3 should be stored separately from incompatible substances (e.g., water, strong oxidants, etc.).
In any case, PBR3 should be transported and stored in accordance with relevant regulations and safety guidelines, and appropriate safety measures should be taken when handling this compound.
The following precautions need to be followed when using phosphorus tribromooxylate (PBR3):
1.Good Ventilation: When using PBR3, ensure that the operating environment is well ventilated to prevent its vapor concentration from being too high.
2.Personal protective equipment: Chemical protective glasses, protective gloves, and a lab coat should be worn when using PBR3 to protect ** and eyes from PBR3 contact.
3.Avoid contact: Avoid direct contact with PBR3 or eyes as it may cause burns.
4.Emergency measures: Immediately after accidental exposure to PBR3, rinse the affected area with plenty of water and seek professional medical help.
5.Storage safety: Store PBR3 away from flammable materials, oxidants and acids, and place clear warning signs in the storage area.
6.Caution in handling: Care should be taken when handling PBR3 to avoid dust, vapor or fog. Wash your hands promptly after operation and avoid accidental ingestion or inhalation.
In all cases, PBR3 should be handled and used in accordance with relevant regulations and safe operating procedures to ensure the safety of yourself and others.