Why freeze dried products should be pre frozen in advance

Mondo Social Updated on 2024-01-28

FD-S series pilot freeze dryer.

Xinyu freeze dryer equipment is a special equipment for lyophilized products. Freeze-drying is the removal of free water and partially bound water adsorbed in the solid lattice space in a low-temperature vacuum environment. Therefore, the freeze drying process is generally divided into five steps, namely pre-freezing sublimation drying (or first-stage drying), analytical drying (or second-stage drying), endpoint judgment and product removal.

This stage mainly plays a fixed role in order to dry the product, which is an extremely critical step. Because if it is not handled properly, it will cause many product molding problems or quality problems, so it is necessary to strictly control the time, temperature and vacuum level of pre-freezing. However, in actual production, the influencing factors of vacuum degree are often ignored in the pre-freezing process.

The pre-freezing temperature is generally within 5 ° below the freezing point, also known as the eutectic point temperature or 10 15 ° below the eutectic point temperature, and the temperature jump point in this process is the appropriate pre-freezing temperature. When the temperature reaches the lyophilization temperature, it is maintained for a period of time, and the pre-freezing time is not fixed, and it can be completely frozen in 2-3 hours, depending on the product load plate area and the nature of the heat transfer medium.

The above content is provided by Xinyu freeze-drying equipment manufacturers according to the network, and it can be ruthlessly exposed.

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