Recently, someone asked Mr. Wang: Can I still use stem cells to repair my ovaries at the age of 46?Can you still have children?Let's share it in this article!
First of all, let's understand a little bitWhat is the mechanism of action of stem cells on the ovaries?
1. Induce follicle growth and increase the quality and quantity of follicles
Mesenchymal stem cells with different transplantation pathways can migrate to damaged target organs, induce follicle growth through differentiation and secretion of growth factors, and upregulate follicle development-related genes, thereby increasing the number of follicles
2. Reduce apoptosis of granulosa cells and improve the microenvironment
Mesenchymal stem cells can improve the ovarian microenvironment and restore ovarian function through homing, directional migration into the ovarian interstitium, reduction of granulosa apoptosis and alleviation of ovarian interstitial fibrosis.
3. Use immunomodulation to inhibit and improve tissue damage
Mesenchymal stem cells also have immunomodulatory functions, which can exert immunomodulatory functions and inhibit inflammation by upregulating the proliferation of Treg cells.
4. Increase ovarian blood supply and induce ovarian vascular growth
Mesenchymal stem cells have paracrine effectsIt induces ovarian vascular growth through growth factors secreted by autocrine and paracrine effects, such as vascular endothelial growth factor.
The above are the four mechanisms of action of stem cells against the ovaries, and at the same time, there are indeed public reports of successful conception through stem cells, and even many cases have been on the official media.
From the feedback received by individuals, the main role of feedback mesenchymal stem cells is as effective as follows:It improves follicle activation and follicle growth in users, and contributes to the long-term recovery of ovarian function, including ovarian blood flow and estradiol levels.
As for "Can I still use stem cells to repair my ovaries at the age of 46?""It really depends on the physical condition, but I personally think that conception is promising.
However, we still need to recognize the limitations of stem cells:
1. There is no drug on the market for stem cells!All stem cell projects are currently done privately;
2. The probability of stem cells repairing the ovaries to achieve the purpose of conception is still relatively low
Stem cells can be said to have lit a bright light, but there are still certain limitations, and they must be used under the condition of rational understanding.