In medical imaging, ground-glass opacity is a common finding.
However, ground-glass opacities do not necessarily represent tumors.
In fact, ground-glass opacity is complex, and a variety of diseases can be manifested as ground-glass opacity (homogeneous disease), especially interstitial lung diseases, which are difficult to diagnose and distinguish by imaging, and even confirmed by needle pathological biopsy.
Therefore, in practical work, it is necessary to closely integrate clinical practice, and cannot be done behind closed doors. Sometimes, history is the answer.
For example, in HIV-positive patients with diffuse ground-glass opacities in both lungs, the possibility of Pneumocystis pneumonia should be considered.
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Some ground-glass nodules may be transient inflammatory lesions, such as partial inflammatory exudation, edema, and inflammatory interstitial thickening of lung tissue, which are absorbed in a short period of time.
For ground-glass nodules with high-risk factors and high-risk imaging features, short-term reexamination and timely intervention should also be noted.
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Ground-glass opacity is caused by thickening of the alveolar wall and increased fluid in the alveolar cavity due to inflammatory cells, edema, fibrosis and other lesions in the lung tissue.
These lesions can be caused by a variety of reasons, such as infections, autoimmune diseases, drug reactions, etc.
Therefore, ground-glass opacity is not just a manifestation of tumors, but a common feature of many diseases.
In the actual diagnosis process, we need to make a comprehensive judgment based on the patient's clinical manifestations, laboratory tests, imaging examinations and other information. For the differential diagnosis of ground-glass opacity, we can refer to the following:
Observe the extent and distribution of lesions: ground-glass opacities may be confined to one lobe or parts of multiple lobes, or may be diffuse. By comparing the imaging manifestations of different parts, we can preliminarily determine the nature of the lesion. Analyze the morphological characteristics of the lesion: the morphology of ground-glass opacities is different, and may appear as different structures such as sheets, strips, and reticules. These morphological features help us distinguish between different types of lesions. Pay attention to the dynamics of the lesion: ground-glass opacities may remain stable over time or change over a short period of time. By regularly reviewing the images and observing the trend of lesions, it helps us to detect potential problems in time. Combination of laboratory tests and medical history: laboratory tests and historical information are of great value in the differential diagnosis of ground-glass opacities. For example, in HIV-positive patients with diffuse ground-glass opacities in both lungs, the possibility of Pneumocystis pneumonia should be considered. For some special types of inflammatory lesions, such as pulmonary hemorrhage-nephritic syndrome, lymphoma, etc., we also need to be vigilant. In short, although ground-glass shadowing is a complex image phenomenon, we cannot talk about grinding color change because of this.
In practical work, we must closely integrate clinical practice, comprehensively analyze all kinds of information, and treat each case rigorously and flexibly.
Only in this way can we provide patients with accurate and timely diagnoses and recommendations to help them get sooner rather than later.