With less than a month to go until New Year's Day, holiday dinners, drinking alcohol, and high-fat diets are inevitable. The reporter learned that the number of patients with acute pancreatitis who come to Jiangsu Provincial Hospital of Traditional Chinese Medicine for treatment on holidays will increase significantly, and the number of acute pancreatitis induced by hyperlipidemia has gradually increased in recent years. Recently, Mr. Li, 40, was admitted to the emergency department of Jiangsu Provincial Hospital of Traditional Chinese Medicine by his family for acute abdominal pain after eating a large amount of barbecue at night. A blood test found that Mr. Li's blood was clearly stratified, with a milky white lipid layer, commonly known as "milk blood", and triglycerides of 5481mmol L, about 24 times the normal value!
Triglycerides soar, inducing severe acute pancreatitis.
Mr. Li, 40, was admitted to the emergency department of Jiangsu Provincial Hospital of Traditional Chinese Medicine by his family because of acute abdominal pain after eating a large amount of barbecue at night. Emergency CT examination showed acute pancreatitis, amylase 871U L, lipase 2427UL, far beyond the normal value, admitted to the Department of Gastroenterology of the Provincial Hospital of Traditional Chinese Medicine. A blood test found that Mr. Li's blood was clearly stratified, with a milky white lipid layer, commonly known as "milk blood", and triglycerides of 5481 mmol l, about 24 times the normal value, total cholesterol 1716 mmol L, about 3 times the normal value, and the diagnosis is hypertriglyceridemia acute pancreatitis.
Mr. Li has a history of hypertension, type 2 diabetes, hyperlipidemia, fatty liver and kidney stones. Acute pancreatitis is a very serious disease with acute onset and rapid development, which can affect organs and systems throughout the body, and progress to severe acute pancreatitis with a dangerous condition and high mortality rate. After admission, due to the aggravation of abdominal pain, shortness of breath, blood pressure drop and other emergencies, the patient was quickly transferred to the intensive care department**, and on the basis of maintaining stable vital signs, plasma exchange, bedside hemofiltration were given to quickly remove chylomicrons in plasma, reduce triglycerides, etc.
Patient plasma exchange, filtered plasma like butter.
*During this period, the patient has high fever, respiratory failure, ascites effusion, etc., and is given anti-infection, ventilator support, puncture and drainage to release ascites, etc. After positive **, the patient's condition improved, and he was transferred back to the general ward of the gastroenterology department, and then ** was discharged. When he was discharged from the hospital, the medical staff of the gastroenterology department repeatedly told Mr. Li to adjust his diet in the future, exercise moderately, work and rest regularly, control his weight, and regularly monitor changes in blood lipids and blood sugar to prevent diseases.
Liu Junlou, deputy chief physician of the Department of Gastroenterology of Jiangsu Provincial Hospital of Traditional Chinese Medicine, introduced that "milk blood", also known as chyle blood, is slick blood, which is the body reminding you that the fat content in the body is too high. Hyperlipidemia is an increase in plasma cholesterol or triglycerides, and in general, hyperlipidemia-induced acute pancreatitis is common in patients with high triglycerides.
Acute pancreatitis itself is a very serious disease, and if not carried out in time** and intervention, it may lead to further aggravation of the condition, and the mortality rate of severe acute pancreatitis is as high as 30%. Mr. Li is overweight, has some underlying diseases such as hyperlipidemia, and does not control his diet, which led to the occurrence of acute severe pancreatitis, but fortunately, it was timely.
How scary is acute pancreatitis?It will eat itself.
The stomach and intestines are the main digestive organs of the human body, but there are multiple organs involved in the whole process of digestion and absorption of food, and the pancreas is one of them. The pancreas is the second largest gland in the human body, which can secrete pancreatic juice and insulin, and has the role of digesting proteins, fats, and sugars, and its main function is to participate in the digestion and metabolism of the human body.
Acute pancreatitis is a local inflammatory response that results in the activation of pancreatic enzymes and acts on pancreatic tissue. Normal pancreatic enzymes digest food, but in the state of acute pancreatitis, pancreatic enzymes will appear in a state of "six relatives do not recognize", not only digesting food, but also digesting their own pancreatic tissue and even the tissues around the pancreas.
The most typical symptom of acute pancreatitis is severe, persistent abdominal pain, particularly epigastric pain, which can affect the lower back. It can be accompanied by symptoms such as nausea, vomiting, bloating, cessation of bowel movements, and gastrointestinal bleeding. Symptoms of hyperlipidemic acute pancreatitis are similar, usually presenting with severe abdominal pain and markedly elevated amylase and lipase, accompanied by elevated lipids.
What is the relationship between hyperlipidemia and acute pancreatitis?What are the triggers?
Nowadays, many people's physical examination reports will indicate "dyslipidemia", hyperlipidemia is an important factor in causing acute pancreatitis, and the results of relevant studies show that if the triglyceride level is greater than or equal to 565mmol L is equivalent to entering the warning line for the prevention of "hyperlipidemic acute pancreatitis";If the triglyceride level exceeds 113mmol L, it is necessary to be highly vigilant for the occurrence of pancreatitis. There are many reasons for acute pancreatitis, simply put, the blood with significantly increased blood lipids is like milk, which is in a hypercoagulable state, which will cause severe microcirculation disorders, thereby causing pancreatic necrosis, leading to acute pancreatitis. Conversely, after the onset of acute pancreatitis, triglyceride levels can be further elevated due to systemic stress response and impaired islet function.
Director Liu Junlou introduced: "Poor diet, hyperlipidemia, alcoholism, obesity, gallstones and pregnancy are all factors that induce acute pancreatitis. Young people often develop improper diet, overeating or excessive alcohol consumptionMany middle-aged and elderly people are related to gallbladder disease. ”
In general, poor lifestyle and diet are closely related to the occurrence of hyperlipidemic acute pancreatitis. Hyperlipidemic pancreatitis has a higher incidence and higher incidence of pancreatic necrosis and organ failure than other causes, and it is necessary to pay attention to controlling blood sugar and lipids and changing life Xi.
How to prevent hyperlipidemic acute pancreatitis?
The key to prevention is to focus on preventing hyperlipidemia.
1 Keep in mind the following "Top 3 Dietary Secrets."
1) Reduce your intake of high-fat foods. High-fat foods are mainly foods with high oil content and fried foods, such as walnuts, peanuts, fatty meats, animal offal, cream products, etc.
2) Cook with less oil. Food production should choose less oil cooking methods, reduce excessive food processing, use less frying, frying and other oily cooking methods, and choose more steaming, stewing, boiling and other methods.
3) Eat a diet with less sugar. Limit sugar intake and eat less sweets;Don't drink or drink less sugary drinks;Reduce the frequency of intake of high-sugar packaged foods: such as biscuits, ice cream, chocolate, etc.;Cooking at home can reduce sugar.
2 Follow the doctor's advice, exercise moderately, and use lipid-lowering drugs correctly.
Moderate exercise not only strengthens the heart and lungs, but also reduces weight and lowers serum triglyceride and cholesterol levels.
For some people with high blood lipids, lipid-lowering drugs should be adjuvant in addition to changing diet and Xi lifestyle habits. For example, drugs that lower serum total cholesterol and LDL-based drugs or drugs that lower serum triglycerides are chosen.
In recent years, some scholars have put forward the concept of "blood turbidity", believing that the occurrence of this disease is mainly attributed to the liver, spleen and kidney. Long-term addiction to wine, cheese, fat and sweetness will hurt the spleen, stomach and viscera, and the water valley will be transported abnormally, and the dampness will become turbid, forming blood turbidity. **The principles include "strengthening the spleen and dissolving turbidity", "dissolving phlegm and invigorating blood", "invigorating blood and removing blood stasis", etc. Poria cocos, Atractylodes macrocephalus, Ze Yuan, Citrus Peel, Hawthorn, Lotus Leaf, Cassia Seed, Salvia Miltiorrhizae, etc. all have obvious lipid-lowering effects, and Chinese medicine compounds such as Erchen Tang, Ze Epsom Tang, Yinchen Wuling San, Gegen Qinlian Tang and so on have significant effects on simple obesity and hyperlipidemia.
Correspondents: Liu Junlou, Shen Qing, Yangtze Evening News reporter Yu Dandan.
Proofread by Xu Heng.