Trillions of microbes live in our bodies, including bacteria, viruses, and fungi. These microorganisms form a complex ecosystem that we call symbiotic flora. With the deepening of microbial genomics research, we have a deeper understanding of the symbiotic microbiota. A large number of gut microbiome studies have shown that the symbiotic microbiota of the human body can affect our health, physique, personality and even life expectancy to a certain extent!
Longevity and health are the goals that human beings have always pursued. No matter where they are, everyone wants to live longer. In recent years, with the advancement of medicine, the lifespan of human beings is indeed gradually increasing, and we have more opportunities to enjoy the beauty of life. However, with the rapid increase in the financial burden of age-related diseases, people still expect to have a vibrant life in their later years, rather than being plagued by illness.
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The secret of a long and healthy life may be hidden in our gut flora, which may rejuvenate us and rejuvenate us.
With the increase of age, the intestinal microbiota will change, the abundance of dominant flora will decrease, the abundance of subdominant flora will increase, and the microbial diversity will gradually decrease. These changes are associated with aging-related deterioration of immune system function and low levels of chronic inflammation, and are accelerated by the progression of aging.
As an important part of the two-way communication between the gut-brain axis, the intestinal microbiota affects the body's hormone secretion, neuromodulation and immune regulation. Disorders of the intestinal microbiota can accelerate the development of immunosenescence and inflammatory aging, destroy the blood-brain barrier, activate glial cells, damage brain function, accelerate aging-related cognitive impairment and behavioral changes, and lead to anxiety, depression and decreased social skills.
Researchers from the APC Microbiome Research Center at University College Cork, Ireland, published a study in the authoritative journal Nature entitled: "Microbiota from Young Mice Counteracts Selective Age-Associated Beh**ioral Deficits".Transplanting the intestinal microbiota of young mice into older mice can counteract aging-related cognitive changes in the brains of old mice to some extent
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It can be seen that fecal microbiota transplantation (FMT) may have the potential for aging-related cognitive decline. The improvement of intestinal flora will play a certain positive role in delaying the aging of the human body.
The gut is not only the beneficial flora in a person's body, but also the human body itself is closely linked. There is a relationship of interdependence and mutual constraint between them. The human body provides a suitable environment for these bacteria to grow, and they maintain the health of the body in a variety of ways.
Taking Bifidobacteria as an example, it has many effects on the human body, such as barrier effect, nutritional effect, immune effect, etc., and can also improve the body's tolerance to radiation. At the same time, the human body also provides a suitable temperature, nutrition and environment for Bifidobacteria.
If the microbiota environment changes, the number of beneficial bacteria decreases, which may lead to various problems in the body, such as constipation or diarrhea. As we age, the microbes that cause chronic inflammation, metabolic disorders, and disease may gradually replace the "friendly" microbes that have beneficial effects on the metabolism and immune system, accelerating the aging of the body.
Therefore, only when the microbiota environment is readjusted, can the body recover its health and slow down the aging rate of the human body.
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The gut microbiota has a profound impact on all aspects of human life, including the immune system, metabolism, hormone balance, cognitive performance, and gene expression. They play a key role in our health and disease, and may even hold the secret to longevity. It is only when we treat and take care of the gut flora that they give back to our healthy body.
In the future, maintaining a healthy gut flora may become a key indicator of healthy aging. Eating right, changing unhealthy lifestyles, and optimizing the composition of the intestinal flora will not only contribute to the health and longevity of individuals, but also to healthy ageing on a global scale. In this way, the realization of the dream of "rejuvenation of old age" will no longer be out of reach.
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