DOTA-ARG-GLY-ASP-SER-PRO-LYS-OH, or DOTA-RGD-SPK, is a polypeptide molecule. The letters and abbreviations in its name represent its amino acid composition and sequence.
Dota is a commonly used peptide crosslinker that binds peptides to radioactive elements or other drugs for targeting** or diagnostics. RGD is a commonly used peptide sequence that binds to integrin receptors on the surface of certain cells, such as V3.
SPK is another peptide sequence that binds to RGD and can increase the stability and hydrophilicity of the peptide, making it easier for cells to take up and internalize.
The DOTA-RGD-SPK peptide molecule has a wide range of applications in tumors** and diagnostics. It can be used as a carrier of radioactive elements or other drugs, and by binding to integrin receptors on the surface of tumor cells, it promotes the uptake and internalization of drugs in tumor cells, thereby improving the best effect. At the same time, it can also be used as a fluorescent probe or magnetic resonance imaging agent for the imaging and diagnosis of tumors.
Storage conditions: Store in a dark, dry environment at a temperature of -20. When dispensing, be sure to make sure it is dry and avoid frequent dissolving and lyophilization processes. Tips: This item is only suitable for scientific research or industrial applications, and is not medicinal or edible, so please be sure to use it with caution. The above is a detailed introduction of dota-rgdspk-oh by XYS, editor of Shaanxi Xinyan Bomei.