A 39 year old man was diagnosed with liver cancer, how did hepatitis B develop into liver cancer?

Mondo Health Updated on 2024-01-31

"My bowels are all blue, and if I had paid attention to it earlier, it wouldn't have been like this. Xiao Chen, 39, was diagnosed with liver cancer in the hospital in his hometown and was full of regret.

Xiao Chen's mother has hepatitis B, and he has also carried the virus since he was a child, but because he was born in the countryside, his family has no concept of hepatitis B, so he has not been able to get **. Until recently, Xiao Chen felt fatigue, abdominal distention, nausea, right upper abdominal distension and pain" and other symptoms, Xiao Chen completely collapsed, and the doctor told her that her alpha-fetoprotein was very high, and the B-ultrasound results showed a solid liver mass, and after further diagnosis, she was diagnosed with liver cancer.

So how does hepatitis B develop into liver cancer?

There are 20 million to 30 million chronic hepatitis B patients in China, and the first step is wrong: not having a "blocking shot" at birth. Xiao Chen's mother is a hepatitis B patient, however, after Xiao Chen was born, he was infected with hepatitis B at birth without a hepatitis B "blocking injection". There are three major ways of transmission of hepatitis B virus: mother-to-child transmission, blood transmission, and sexual transmission, and most people's hepatitis B belongs to the first type, that is, at birth, it is transmitted due to broken **, mucous membranes or placenta in contact with the mother's blood, so if the mother is positive for hepatitis B surface antigen (HBSAG), the baby should be injected with a "blocking needle" within 24 hours (preferably within 12 hours) after birth.

Blocking needle, including two kinds of injections, one is the hepatitis B vaccine that every Chinese child will take after birth, which can stimulate the body's immune cells and produce surface antibodies, and the other is that hepatitis B immunoglobulin (HBig) can play a protective role in the interval before the vaccine takes effect, hepatitis B vaccine hepatitis B immunoglobulin combined immunization method is currently the most effective measure to block mother-to-child transmission, with a blocking rate of about 90%, unfortunately, Xiaojie missed these two shots.

Step 2: Never go to the hospital for a check-up. After being infected with hepatitis B, Xiao Chen's tragedy continued, and because there was no discomfort, the parents did not take it seriously. When everyone thought it was nothing, the condition was quietly deteriorating, why was there no sign before?

This is because the liver is a "silent organ" simply put, that is, it will not be painful, its pain nerves are mainly distributed in the surface of the liver capsule, bile ducts, etc., and there is almost no inside the liver, even if there is an early lesion, it will not make people feel pain, until the tumor develops to the middle and advanced stages, the patient will have symptoms such as right upper abdominal discomfort, abdominal pain, jaundice, fatigue and digestive malabsorption, at this time, the best time has often been lost.

Throughout the process, the hepatitis B virus continuously attacks the liver, causing hepatocyte necrosis, liver damage, and if the body's immune cells are unable to kill the hepatitis B virus, it will evolve into chronic hepatitis B;Liver tissue repeatedly produces inflammation and necrosis, self-repair, continuous fibrosis, and finally gradually forms liver cirrhosis, from chronic hepatitis B, to liver cirrhosis, to liver cancer, which is the most common "hepatitis B trilogy".

About 80% and 90% of liver cancer patients have a background of hepatitis B and liver cirrhosis, and it usually takes 10 to 15 years for male patients to develop from hepatitis B to cirrhosis and then to liver cancer. Here is an important reminder: If you or someone around you is infected with hepatitis B, you should check it as soon as possible, really don't wait until you are uncomfortable before going to the doctor, how often to check, what items to check, you can take a look at this **, refer to the content of this **.

The third step is wrong: I think it's just a "little three yangs" that don't need to be treated.

There are also some hepatitis B patients who do not go, because they feel that they are just "little three yang" and do not need **, but in recent years, the concept has changed, and now they are more advocating the expansion of antiviral**, according to the latest guidelines for the prevention and treatment of chronic hepatitis B, 2022 edition) Even if they only carry hepatitis B virus, as long as they meet the following two categories, they must start antiviral in time**

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