Polydimethylsiloxane is a hydrophobic silicone material, which can be used for the brewing of medicine and food, and the defoaming of fermentation time. Because it is non-toxic and does not cause physiological reactions in the human body, it is also used as a medical antifoam for acute pulmonary edema and flatulence**. The substances called silicones (or silicone oils) in pharmaceutical monographs are a general term for a class of organosilicon oxidation polymers. Dimethicone is only one of its most commonly used agents. In addition, there are ethyl silicone oil, methyl phenyl silicone oil, wax silicone oil and so on. In the tablet polishing insect wax, a small amount of this product is often added to enhance the brightness and moisture resistance of the sheet. In ointment, this product is an ideal hydrophobic matrix because it has good lubricity, easy coating, does not stain clothes, and does not hinder the normal function of the ointment. It is often combined with oily substrates to make protective ointment, which is used to prevent irritation or corrosion of water-soluble substances, acids, lyes, etc.
Dimethicone can be mixed with surfactants such as lanolin, stearyl alcohol, cetyl alcohol, glyceryl monostearate, Tween, span and other surfactants as an emulsion matrix. Thin film formers such as PVP, PVA and cellulose derivatives are added to this product to enhance its protection. The release and penetration of the drug is faster than that of gunetin, lanolin and petrolatum.
According to the different kinematic viscosity, it can be divided into 2050.100.200.350.500.750.1000.12500.30000 ten models.
The kinematic viscosity of polydimethylsiloxane (General rule 0633 first method, capillary inner diameter 2mm) is 500 1000mm s at 25, and the viscosity is 1000mm s, and the second method is used when it is above and above.
ST204C automatic dual-purpose kinematic viscometer is designed and manufactured in strict accordance with the 2020 Chinese Pharmacopoeia General Chapter 0633 of the first method of Pin's capillary viscosity determination method and the second method of Uuc's capillary viscometer determination, and uses the relative method to measure the time required for a certain volume of liquid to flow through the capillary under the action of gravity to obtain the kinematic viscosity of the fluid. It has a series of automatic functions such as automatic constant temperature, automatic extraction, automatic timing, automatic calculation, automatic printing, automatic cleaning, automatic drying, etc., and only needs to click to start once to complete the test when using.