This article is from "Nankai Sun Pharmacist", which is used for medical science popularization for reference. Xuesaitong is a commonly used Chinese patent medicine for blood circulation and stasis in clinical practice, its main ingredient is Panax notoginseng saponins, which are composed of ginsenosides and notoginseng saponins, which have the effect of invigorating blood and removing stasis, clearing the veins and activating the veins, and are mainly used in the recovery period of stroke caused by cerebral stasis, and the symptoms are hemiplegia, hemiplegia, crooked mouth and tongue, tongue is strong or silent, and can also be used for angina pectoris of coronary heart disease with blood congestion obstruction, chest paralysis, chest pain, palpitation, purple tongue or ecchymosis, which can only be used after syndrome differentiation in traditional Chinese medicine, not the main ** Drugs can only be used as a combination adjuvant on the basis of standardization.
The main active ingredient of Xuesaitong is notoginseng saponins, there is a clear dosage, some drug manufacturers have carried out cell experiments and animal experiments, these basic studies have found that notoginseng saponins can dilate cerebral blood vessels, increase cerebral blood flow, improve cerebral blood circulation, correct the pathological state of acute cerebral ischemia and acute myocardial ischemia, have a protective effect on brain injury caused by hypoxia, and can increase red blood cells and hemoglobin in the blood, prolong the time of hypoxia tolerance, inhibit lipid deposition, regulate blood lipids, antiplatelet aggregation, inhibit atherosclerotic inflammatory reaction, anticoagulation, prevent arteriovenous thrombosis, and enhance the phagocytosis of the reticuloendothelial system, promote the production of antibodies, regulate the body's immune function, and maintain immune balance.
Panax notoginseng saponin is a calcium ion antagonist, mainly by inhibiting the influx of calcium ions on vascular smooth muscle cells, so that the total amount of calcium ions in the cell is reduced, thereby dilating the peripheral arterioles, reducing peripheral vascular resistance, and playing a hypotensive role. Issues such as safety are not yet well understood, and further human clinical trials are needed to confirm them.
In short, Xuesaitong is a commonly used Chinese herbal medicine in clinical practice, with the effect of invigorating blood circulation, and is mainly used in clinical use for the sequelae of cerebral infarction and the adjunct of stable angina pectoris of coronary heart disease, mainly as a combination drug on the basis of standardization, Panax notoginseng saponins have a variety of pharmacological activities, such as anti-cerebral ischemia, inhibition of lipid deposition, anti-platelet aggregation, anticoagulant, Anti-inflammatory, etc., in addition, notoginseng saponins have the effect of dilating peripheral blood vessels and lowering blood pressure, which has been confirmed by animal experiments, but there is a lack of human clinical trial data, and its safety, efficacy and long-term benefits are still unknown, and it is not recommended for **hypertension.