Chinese name: phospholipid polyethylene glycol polypeptide.
Product Name: dspe-peg-rgd
Molecular weight: 1k, 2k, 34K, 5K, 10K, 20K (can be customized on demand).
Material properties: white solid or powder, depending on PEG (polyethylene glycol) molecular weight.
Solubility: soluble water and some organic solvents.
PEG molecular weight: 1000, 2000, 5000, 10000, 20000
Storage: Long-term storage of materials needs to be protected from light, and -20 refrigerated storage under dry conditions to avoid repeated freezing and thawing.
Uses: Only for scientific research, not for human body.
DSPE-PEG-RGD is a very valuable drug carrier, which has a wide range of applications in the field of drug delivery due to its specific targeting and good biocompatibility. DSPE-PEG-RGD is composed of DSPE (distearoylphosphatidylethanolamine), PEG (polyethylene glycol) and RGD (arginine-glycine-aspartic acid) and is a very effective drug carrier.
The targeting of DSPE-PEG-RGD is mainly due to the RGD sequence, which specifically binds to the V3 integrin on the surface of tumor cells, thereby enabling tumor targeting**. In addition, DSPE-PEG-RGD can also achieve directional drug delivery by taking advantage of the "hypoperfusion" phenomenon of tumor tissue through passive targeting.
The biocompatibility of DSPE-PEG-RGD is mainly due to its constituent components DSPE and PEG. DSPE is a phospholipid with good biocompatibility, while PEG has the advantages of high water solubility, non-toxicity and good biocompatibility. Therefore, DSPE-PEG-RGD has good biocompatibility in vivo, which can effectively reduce the immunogenicity of drugs to the body and reduce the occurrence of adverse reactions.
In addition, DSPE-PEG-RGD also has good drug delivery properties. It can be used as a drug carrier to accurately deliver drugs into tumor tissues, thereby improving the efficacy of drugs and reducing the efficacy of drugs At the same time, DSPE-PEG-RGD can also achieve sustained and controlled release of drugs by controlling the release rate and release mode of drugs, so as to better meet the needs of clinical practice.