This article is from "Nankai Sun Pharmacist", which is used for medical science popularization for reference. The 4 clever combinations of Xuefu Zhuyu Pill are summarized in one article
1. Xuefu Zhuyu Pill + Flunarizine: migraine.
Xuefu Zhuyu Pill comes from the book "Medical Forest Correction Error" written by the famous Qing Dynasty medical scientist Wang Qingren, and the drugs contained in the formula include Taohong Siwu Tang (peach kernel, safflower, angelica, Chuanxiong, Shengdi, red peony), Siyi San (Bupleurum, Jihu, licorice, red peony) and bellflower, oxknee and other medicines. Among them, red peony, hyssop, peach kernel and safflower are all important medicines for blood circulation and blood stasis, dredging blood vessels, and can increase the effect of invigorating blood and nourishing blood, dispelling wind and meridians, regulating qi and relieving pain; Platycodon, citrus aurantium, and Bupleurum can soothe the liver and regulate qi, widen the chest and relieve depression, so that qi can flow blood, and qi can live blood; The combination of various medicines can play the role of invigorating blood and removing blood stasis, dissolving depression and relieving qi, and relieving pain. Modern pharmacological studies have proved that Xuefu Zhuyu Pill has the effects of dilating blood vessels, improving microcirculation and blood rheology, reducing blood flow resistance, increasing blood flow to ischemic organs, anti-atherosclerosis and reducing blood lipids, etc., and has an analgesic effect. Oxknee, peach kernel and safflower can inhibit platelet aggregation, dilate blood vessels, prevent thrombosis, protect cardiovascular and cerebrovascular vessels, and nourish nerves, and can better regulate the internal environment and cranial nerves of the human body, and play an analgesic and antispasmodic role. The active ingredient of Chuanxiong can improve the contractile function of cerebral blood vessels, inhibit the spasm of vascular smooth muscle, reduce vascular resistance, increase blood flow to brain tissue, and promote blood circulation.
Flunarizine is a calcium ion antagonist and is a commonly used drug for migraine in clinical practice. It can inhibit platelet release, cut off calcium ions for transmembrane influx, and ultimately prevent migraine attacks; It can prevent arteriolar spasm, prevent the release of pain-causing substances, and achieve the purpose of relieving the condition.
After Xuefu Zhuyu Pill combined with flunarizine** migraine, the duration of the patient's headache attack was shortened, the number of headache attacks decreased within one month, and the headache index decreased significantly.
2. Xuefu Zhuyu Pill + Shengmai Capsule: angina pectoris for coronary heart disease.
Modern pharmacological studies have shown that Shengmai San can reduce myocardial oxygen consumption and glycogen metabolism, promote synthesis, have a stable and long-lasting cardiotonic effect, and can improve the function of the whole body.
Angelica, Chuanxiong, peach kernel, safflower, angelica, red peony in the blood stasis pill prescription invigorate blood circulation and dispel stasis; Bupleurum and Citrus aurantium husk relieve qi and relieve depression, bellflower induces qi upward, oxknee helps blood stasis to go down, and the combination of various medicines not only carries out blood stasis, but also relieves qi stagnation, qi stasis is removed, blood stasis is cleared, and heart and blood are unobstructed. Xuefu Zhuyu Pill has the effects of dilating blood vessels, anticoagulation, inhibiting platelet aggregation, reducing blood viscosity, preventing thrombosis, reducing myocardial oxygen consumption, and improving microcirculation.
Shengmai Capsule combined with Xuefu Zhuyu Pill can reduce the number of angina attacks, shorten the duration of angina, improve electrocardiogram, significantly alleviate the clinical symptoms of angina patients, significantly reduce CRP level, and improve blood lipid status (HDL level). These results suggest that Xuefu Zhuyu Pill combined with Shengmai Capsule can inhibit inflammation, stabilize plaque, prevent thrombosis and effectively reduce the occurrence of coronary events.
3. Xuefu Zhuyu Pill + Methylcobalamin: Diabetic peripheral neuropathy.
Methylcobalamin is one of the active forms of vitamin B12 in the body. It can promote the formation of nucleic acids, proteins and lipids in nerve cells, thereby repairing damaged nerve tissue, promoting myelination and axon regeneration, and is routinely used in clinical practice for peripheral neuropathy. However, methylcobalamin alone does not improve the ischemic and hypoxic state of nerve tissue.
Xuefu Zhuyu Pill is composed of peach kernel, safflower, red peony, Chuanxiong, citrus aurantium, bupleurum, bellflower, angelica, rehmannia, hyssop, and licorice. In addition, modern pharmacological research has the effect of anticoagulation and lipid reduction, improving vascular endothelial function, reducing the viscosity of whole blood, relieving vasospasm, and improving microcirculation, thereby improving the ischemic and hypoxic state of diabetic peripheral nerves, giving life material energy to the sub-tissues, so that they have the ability to change the pathological state and restore health. At the same time, it also illustrates the important role of traditional Chinese medicine in peripheral neuritis. However, Xuefu Zhuyu Capsule cannot directly repair the damaged nerve tissue, and must be combined with methylcobalamin to have a better effect.
4. Xuefu Zhuyu Pill + Xiaoyao Pill: abnormal mood during menopause.
Xuefu Zhuyu Pill is in line with the ** of "Qi and Blood", medicinal Bupleurum, Citrus aurantium, Platycodon soothes the liver, and widens the chest and separators; peach kernel and safflower invigorate blood circulation and dispel blood stasis; Angelica, Rehmannia and Red Peony cool blood to invigorate blood and nourish blood; Chuanxiong blood qi medicine, walking but not guarding, combined with the oxknee to lead the meridian to the lower Jiao Palace. Xiaoyao Pill is made of Bupleurum, white peony, and peppermint to help the upper liver to soften the liver, nourish the liver, and soothe the liver, taking into account the foundation of liver yin; Atractylodes macrocephalus and Poria cocos invigorate qi and strengthen the spleen, replenish the driving force of blood running in the vasculature, and correct the foundation of "qi deficiency and stasis". Peppermint is cool and refreshing. The combination of the two can not only promote qi, invigorate blood and remove stasis, but also nourish qi and nourish blood and relax the mind. It makes the qi and blood lively, the blood is flowing, the consciousness is clear, and the heart is refreshing.
Modern pharmacological research has confirmed that Xuefu Zhuyu Pill has the effects of improving microcirculation, reducing blood viscosity, reducing blood lipids, anti-thrombosis, liver protection, and analgesia. Xiaoyao Pill can fight against the immune dysfunction and low immunity of model animals, which is not only related to the specific improvement of immunity by the ingredients contained in the formula, but also related to the compatibility of various medicines, from the central, neuroendocrine, immune and other ways to regulate and improve the body's immunity.
The combination of the two can promote blood circulation, regulate endocrine, enhance immunity, improve the psychological endurance of patients, and improve the quality of life of patients.