Chinese name: phospholipid polyethylene glycol cyclooctyne.
Product Name:dspe-peg-dbco
Synonyms: dbco-peg-dspe
Molecular weight k, 2k, 34K, 5K, 6K, 7K, 10K, 20K (on demand).
Storage conditions: -20
Uses: For scientific research only, not for human use.
DSPE-PEG-DBCO is a unique reagent for biomedical research and belongs to the category of a usable crosslinker for click chemistry macromolecules. The name DSPE-PEG-DBCO consists of several parts, each with its specific function and importance.
DSPE, short for distearoylphosphatidylethanolamine, is a component commonly used in liposomes and other nanoparticles to increase the stability and biocompatibility of membranes.
PEG is an abbreviation for polyethylene glycol, which is a polymer that has a wide range of applications in the biomedical field due to its unique physicochemical properties. PEG can increase the solubility of macromolecular crosslinkers in water and reduce immunogenicity, thereby improving the efficacy and safety of the drug.
DBCO, short for dibenzocyclooctyne, is a cyclic alkyne hydrocarbon that can undergo a highly efficient, copper-free click chemistry reaction with molecules containing azide groups. This reaction is ideal for performing in living tissues as it does not require the addition of any metal catalysts.
In summary, DSPE-PEG-DBCO is a biomedical reagent with broad application prospects. By combining liposomal technology, polymer modification, and click chemistry, this macromolecular crosslinker is expected to play an important role in future drug discovery and medical diagnostics.