Chinese name: phospholipid-polyethylene glycol-cholesterol
Product Name: dspe-peg-cls
Synonyms: cls-peg-dspe
CAS Number: 57-88-5
Molecular weight k, 2k, 34K, 5K, 6K, 7K, 10K, 20K (on demand).
Storage conditions: -20
Uses: For scientific research only, not for human use.
DSPE-PEG-CLS is composed of phospholipids, polyethylene glycol, and cholesterol, with DSPE being a derivative of phosphatidylcholine with a zwitterionic structure that can combine with drugs to form liposomes. Polyethylene glycol is a long-chain polymer that can increase the solubility and stability of drugs and reduce their toxicity and irritation. Cholesterol can enhance the physical stability of liposomes, improve the efficacy of drugs and lower them***
DSPE-PEG-CLS has a wide range of applications in drug delivery systems, and can be used to deliver bioactive substances such as small molecule drugs, proteins, and genes. It controls the rate and amount of drug release by encapsulating the drug in liposomes, so that the drug can reach the target site more efficiently and play its role. At the same time, DSPE-PEG-CLS can also improve the immunogenicity and stability of drugs by modifying the polyethylene glycol chain on the surface, and reduce the clearance and destruction of drugs in the body.