Benbromarone is a good medicine to promote the excretion of uric acid from the kidneys, but when eating it, you must pay attention to 6 contraindications, otherwise it will not only have no effect, but also be very dangerous.
1. Patients with liver disease and patients who drink too much alcohol should use with caution
Benbromarone is a serious hepatotoxicity, so patients with liver disease and excessive alcohol consumption must be used with caution, and the health of the liver should be closely monitored during the medicationIf there is an increase in aminotransferases, fatty liver, jaundice, loss of appetite, etc., the drug should be discontinued immediatelyand avoid taking it at the same time as other drugs that may also cause liver toxicity.
2. Alkalize urine during taking the drug
During the period of taking the drug, the urine should be simplified as much as possible, after taking benzbromarone, a large amount of uric acid in our body will be excreted through the urine through the kidneys, in order to avoid the formation of urate in our kidneys, stones, so in order to protect the safety of the kidneys, we can take drugs such as sodium bicarbonateMaintain the pH of the urine at 62~6.Between 9 and once more than 70 should be discontinued immediately.
3. Drink plenty of water
It is necessary to drink more water, one is to dilute the concentration of uric acid in the kidneys and avoid the production of crystals, and the other is to urinate more, so that uric acid can be excreted more from the body.
4. Do not take it during gout attacks
Do not use it temporarily during an acute attack of goutFailure to do so will aggravate the condition.
5. It can be taken with colchicine
It can be taken with colchicine or some non-steroidal anti-inflammatory drugsIt can prevent the pain of gout attacks
6. Patients with renal insufficiency should be used with caution
It is best not to use it in patients with renal insufficiency or impairment, as well as in patients who have already developed kidney stones.
the end
In general, benzeneBromarone is a drug that promotes uric acid excretion and is not suitable for patients with excessive uric acid production, and benzbromarone generally needs to be used according to kidney function, kidney stones, etc. For example, patients with moderate to severe renal insufficiency, hydronephrosis, polycystic kidney disease, or kidney stones should be used with caution or avoided. Moreover, the use of benzbromarone generally requires drinking more water, keeping the urine output above 2000ml, and alkalizing the urine to keep the pH at 62~6.9. Liver and kidney function should be tested at least once a month after medication.