Introduction: Cushing's syndrome, a seemingly unfamiliar medical term, is actually not far away. It is a disease caused by hormonal imbalances in the body that can lead to a range of serious health problems. This article will demystify Cushing's syndrome and take you to understand the causes, symptoms and methods of this disease.
1. Introduction to Cushing syndrome.
Cushing's syndrome, also known as hypercortisolism, is a clinical syndrome caused by excessive secretion of glucocorticoids by the adrenal cortex over a long period of time due to a variety of causes. This condition causes abnormalities in various systems of the body, which seriously affects the quality of life of patients.
2. Causes of Cushing syndrome.
Pituitary Cushing syndrome: This is the most common type, accounting for about 60% to 70% of Cushing syndrome. Pituitary adenomas secrete too much adrenocorticotropic hormone (ACTH), causing the adrenal cortex to hyperplasia and secreting too much cortisol.
Adrenal Cushing syndrome: accounts for about 20% to 30% of Cushing syndrome. Tumors or hyperplasia of the adrenal glands cause excessive cortisol secretion on their own.
Bilateral adrenal nodular hyperplasia independent of ACTH: about 10% of cases of Cushing syndrome. In this condition, the adrenal cortex proliferates and secretes excess cortisol, but is not regulated by ACTH.
Ectopic ACTH syndrome: about 5% of Cushing syndromes. In this case, tumors in other parts of the country secrete ACTH or an ACTH-like substance, which stimulates the adrenal cortex to secrete too much cortisol.
3. Symptoms of Cushing's syndrome.
Central obesity: the face is rounded, the back is hypertrophied, the waist is wide and the abdomen is spherical and bulging, and the limbs are relatively thin.
*Purple striae: It is more common in the ribs, chest and abdomen, outer buttocks, inner and outer thighs, armpits, popliteal fossa, etc. on the trunk.
High blood pressure and low blood potassium: Long-term hypertension may lead to cardiovascular and cerebrovascular lesions, and low blood potassium may cause muscle weakness, periodic paralysis and other symptoms.
Diabetes mellitus and impaired glucose tolerance: about half of patients have impaired glucose tolerance, and about 20% have overt diabetes.
Osteoporosis: prone to fractures and low back pain.
4. Cushing's syndrome.
Cushing syndrome is mainly performed against the methods of surgical removal of the tumor, drugs and radiation. The specific ** protocol should be developed according to the patient's specific situation and the doctor's recommendation.
V. Conclusion. Cushing syndrome is rare, but its harm should not be underestimated. Understanding the causes, symptoms, and methods of Cushing's syndrome can help us better prevent and respond to the disease. If you or someone close to you has similar symptoms, please seek medical attention promptly so that you can get a professional diagnosis and**. At the same time, we should also pay attention to physical health, maintain good living habits, and prevent the occurrence of diseases.