Application of microfluidic homogenizer in microencapsulation technology

Mondo Technology Updated on 2024-02-01

With the help of polymer polymerization technology, the solid or liquid material is coated with a film-forming material to form tiny particles, and the obtained tiny particles are called microcapsules, and the size of the general particle diameter is 2 1000 microns.

It has the ability to change the appearance and properties of the substance, as well as to prolong and control the release of the substance in the membrane, so that the encapsulated substance has stronger environmental stability.

It has a series of advantages such as small size, large specific surface area, good stability of finished product and good biocompatibility.

It is widely used in coatings, medicine, food, pesticides and fertilizers and other fields.

It usually consists of a wall material and a core material.

The film-forming material that is coated in the outer layer is called the wall material, which can be a natural or synthetic polymer compound, or a small molecule inorganic compound.

Generally speaking, oil-soluble core materials need water-soluble wall materials, and water-soluble core materials need to choose oil-soluble wall materials.

Common structure of microcapsules.

According to its material properties, the mechanism of cyst wall formation and the encapsulation conditions, it can be divided into physical method, chemical method, physical chemical method and other microencapsulation methods.

Microcapsules are common wall materials and their advantages and disadvantages.

The principle of air suspension spraying method is to use the strong air flow of the fluidized bed to suspend the core material particles in the air, and then use the nozzle to spray the wall material solution that has been adjusted to the appropriate viscosity on the surface of the core material particles, and finally volatilize the solvent in the wall material by increasing the temperature of the strong air flow.

Extrusion method extrusion method usually refers to the pore film extrusion method, that is, under low temperature conditions, the emulsion formed by the core material and wall material is extruded through the pore film, and when the wall material is in contact with the dehydrating agent, it will be dehydrated and hardened into microcapsules.

Molecular embedding method Molecular embedding method is mostly used in the food industry, which can microencapsulate oils, pigments, flavors and vitamins and other substances, and its principle is to use the hollow and hydrophobic internal structure of the cyclodextrin carrier to embed the hydrophobic core materialThe droplet size of the core material is consistent

Relying on its unique cavity structure, the microfluidic homogenizer uses a high-pressure power section that can provide stability for processing, ensuring that the droplet size of the core material is consistent and the peak shape distribution is good. It is conducive to the molecular embedding method in microencapsulation technology.

The integrated electric axis drives the micro-jet homogenizer.

The microfluidic homogenizer is used to treat the microencapsulated flavor, which is efficient, which can alleviate the volatilization of the flavor to the greatest extent and avoid the decline of the fragrance threshold. It can be seen that there are no large particles on the bottle wall that are obvious before and after treatment, and the effect is obvious.

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