About why people get cancer. There are many different ways to say it. Some people say that in the long process of evolution, the average age of human beings is also the same.
Twenty or thirty years old, so the factory setup and warranty time is limited. But the increase in the average life expectancy of humans has pushed body parts beyond the boundaries of use, and uncontrolled cancer cells have come as an accident. It is also said that about 20 billion cells in the adult body die according to the instructions every day, but there are always some cells that are unwilling to be bound by fate and finally break free from the shackles and escape from death through struggle. And the tumor is the collection of them coming together against fate. But aside from feelings and deductions, the root of cancer is a group of tumor cells that have obtained unlimited proliferation ability due to genetic mutations.
More than 50 years have passed since 1971, when mankind officially declared war on cancer, and although we have not been able to bridge the gap in overcoming cancer, the progress of science and technology has really helped us find a bridgehead with hope to cross this trench. Immunization** is the first ray of light in recent years. Whether it's by suppressing immune checkpoints, getting the immune system that has been hypnotized by cancer cells back up and working, or genetically engineering T cells to assassinate specific types of cancer cells, or developing new T cell receptors and natural killer (NK series) cells**, the outlook for cancer** is becoming more and more optimistic.
The development and operation of cancer vaccines has given us the confidence to announce for the first time that we want to eradicate a cancer on a global scale. Molecular targeting** is another powerful technical route. It can not only provide precise guidance, but also solve a certain cancer with a specific mutation with high accuracy and small accuracy; It can also target the common problems of cancer development, inhibit the growth of tumor blood vessels, cut off the signal transmission of tumor cells, and overcome the problem of tumor drug resistance. The most important thing is that immunity and molecular targeting are not two parallel lines, they can be combined, or they can be wonderful at different stages, bringing the least harm and the greatest help to patients. And in addition to these front-line fighters, a large number of auxiliary forces are also thriving!
Liquid biopsy technology can quickly detect early signs of cancer and its subtypes through blood testing, so as to achieve early intervention and precise treatment; For whether the surgery is clean or not, and whether there are signs of cancer, liquid biopsy can also give an authoritative answer. Gene editing technology has given us the opportunity to repair genes and turn cancer cells to change their ways. And if the object of our editing and modification becomes immune cells, then we can build a rapid anti-cancer army, quietly sneak behind enemy lines, and eliminate cancer cells cleanly.
The ability to understand, generalize, and integrate provided by artificial intelligence and big data gives us hope to thoroughly integrate the knowledge and discoveries about cancer accumulated around the world over the past decades, correctly analyze each of the patient's examination reports and imaging data, and then formulate a truly effective personalized plan for each patient. Of course, the intervention of artificial intelligence can also greatly accelerate the development of new drugs and the discovery of new cancer markers.
In addition, our knowledge of the gut microbiome is also expanding our means of intervening in cancer. We now know that gut microbes are closely related to digestive cancers such as esophageal, gastric, and colorectal cancers, and that the microbial community can intervene in the progression of cancer by influencing the host immune system.
Therefore, by regulating the intestinal flora, we actually have every hope to achieve the dual effect of cancer prevention and ** cancer. I have always believed that conquering cancer is the biggest research topic in the field of medicine in this century; And the significance of this event for humanity is likely to be as important as the discovery of microorganisms and antibiotics. It was the discovery and use of antibiotics in the last century that nearly doubled human life expectancy; And once we have the ability to tackle cancer, the average healthy life expectancy of human beings will hopefully gradually approach the extreme value of genetic limitation; Human society and human civilization will surely open a new chapter. I am an optimistic technologist, and I always firmly believe that as long as we keep our senses, the development of technology will definitely bring greater help to human health!
Reference: North Shore Kellogg Cancer Center blogyerbba.com/targeted-drugs-for-metastatic-breast-cancer-full-list-2020/frontlinegenomics.com/new-ai-tool-could-predict-lung-cancer-recurrence/