The heart and mouth hurt, tearing and tearing, and the upper abdomen hurt, as if a fire was burning; When you are hungry and at night, this abdominal pain worsens and is relieved after eating; When it is cold, I get sick, which is more accurate than the weather forecast; Bloating, belching, pantothenic acid, nausea, vomiting, these symptoms of indigestion are recurring.
These are all symptoms experienced by patients with duodenal ulcers. It has become one of the common and frequent diseases in the Chinese population, and it is also the most common disease of peptic ulcer. It usually occurs at the turn of autumn, winter and spring, and is more common in men than in women.
Duodenal ulcer is closely related to abnormal gastric acid secretion, Helicobacter pylori (HP) infection, non-steroidal anti-inflammatory drugs (NSAIDS), irregular lifestyle and diet, work and external stress, smoking, alcohol consumption, and psychosocial factors. It mostly occurs in the duodenal bulb, with the anterior wall being the majority, followed by the posterior, inferior, and superior walls.
What are the reasonsLeads to twelveFinger ulcers?
1. Excessive gastric acid secretion.
The digestion of gastric acid and pepsin is one of the causes of duodenal ulcer, and the secretion of gastric acid in patients with duodenal ulcer is significantly increased.
2. The defense mechanism of the duodenal mucosa is weakened.
The patient's gastric emptying is accelerated, and the effect of inhibiting gastric acid is weakened, which increases the acid load in the lumen of the duodenal bulb, resulting in mucosal damage and ulcer formation.
3. Helicobacter pylori infection.
Marshall and Warren were awarded the 2005 Nobel Prize in Medicine for successfully culturing Helicobacter pylori (HP) in 1983 and proposing that its infection play a role in the pathogenesis of peptic ulcers. Helicobacter pylori infection is an important cause of peptic ulcer **, and is vividly likened to "no pH (acid) no ulcer, no HP and no **", but the exact mechanism still needs to be further confirmed.
4. Genetic factors.
Some patients have a family history of the disease (in first-degree family members), suggesting a possible genetic involvement, but this is not well understood.
Duodenal ulcer
The harm caused by not being timely
1. Ulcer perforation.
Duodenal ulcer perforation refers to the appearance of ulcerative lesions in the duodenal area, when the ulcer invades the duodenal muscular, submucosal muscle, and the depth is relatively deep, the phenomenon of intestinal perforation will occur. Clinically, duodenal perforation will occur, severe epigastric pain will occur, and some people will even have gastrointestinal bleeding.
2. Ulcer bleeding.
In general, in the active stage of ulcer disease, there is a small amount of bleeding in the lesions, so there is occult blood in the stool. When duodenal ulcer bleeding is more, patients have symptoms such as black stool, palpitation, dizziness, sweating, poor mental state, etc., and all aspects of function will also decline, long-term bleeding can cause moderate and severe anemia, and there will be a risk of shock and sudden death if not timely, such patients are recommended to go to the hospital as soon as possible, and need to be hospitalized if necessary**.
3. Pyloric obstruction.
Active duodenal ulcer is reversed, resulting in inflammation, edema, spasm of the pylorus and duodenal bulb, temporary gastric emptying disorder, and with the development of lesions, ulcer scar formation, which can eventually lead to pyloric and duodenal bulb scar stenosis and form persistent obstruction.
The following symptoms may occur after the obstruction is formed:
Clause. 1. Epigastric pain and bloating that worsen after eating.
Clause. 2. Repeated vomiting, vomit is overnight food, yellow-green bile. Abdominal pain and bloating may be temporarily relieved after vomiting.
Clause. 3. Patients with long-term vomiting dare not eat or vomit severely, resulting in malnutrition, dehydration, electrolyte disorders, and in severe cases, coma and shock.
Clause. Fourth, some patients have emaciation, dryness, poor elasticity, bulge of the upper abdomen, and some can see gastric peristalsis waves from left to right, and the sound of water oscillation can be heard when the hand is pressed on the upper abdomen or the body position is changed, also known as the sound of vibrating water.
Duodenal ulcer
What are the ways in which it can be diagnosed?
In the diagnosis of duodenal ulcer, the diagnosis can generally be made with the help of 13C urea breath test or 14C urea breath test, urease test, gastroscopy, X-ray barium swallow examination, etc. Patients will have different clinical symptoms due to different **.
Intestinal problems can be too big or small to ignore. If you feel unwell, you still need to check it in time, ** On weekdays, you must also have a regular schedule, eat healthily, live a healthy life, and don't let stomach problems entangle you.