5-p-nitrophenyl furfural is a yellow to orange crystal with the molecular formula C11H7NO4 and a molecular weight of 21318。Its CAS number is 7147-77-5 and its chemical name is 5-(4-nitrophenyl)furan-2-carbaldehyde. The compound has a distinctive aromatic odor and is soluble in organic solvents such as ethanol, ether and chloroform, and insoluble in water.
The synthetic route of 5-p-nitrophenyl furfural is usually obtained by the condensation reaction of nitrobenzaldehyde and butanedione under alkaline conditions. The reaction is carried out at the appropriate temperature and pH conditions, and the target product is generated and purified by crystallization to obtain a high-purity product.
The methods for the preparation of 5-p-nitrophenyl furfural include traditional chemical synthesis methods and microchannel continuity methods. While traditional chemical synthesis methods require a large number of reagents and long reaction times, the microchannel continuous method can improve reaction efficiency, reduce waste generation, and facilitate scale-up.
5-p-nitrophenyl furfural has a wide range of applications in the field of organic synthesis, and can be used as an intermediate in organic synthesis for the synthesis of various oxygen-containing heterocyclic compounds. In addition, the compound can also be used as a raw material in dyes, pharmaceuticals and pesticides.
Microchannel technology is increasingly used in the field of chemical synthesis, which can effectively improve reaction efficiency, reduce waste emissions, and have better reaction control performance. In the future, with the continuous development of microchannel technology, the production of 5-p-nitrophenyl furfural will be more environmentally friendly, efficient, and expected to achieve industrial production.