Many male compatriots think:
I have no problems living as a couple, so I will not have problems having children."
I went to the hospital for a routine check-up, and the results were normal, and there was definitely no problem with fertility."
My brothers have given birth normally, and my inability to have children must be the reason for my wife".
Is this really the case?
Normal sexual function ≠ normal fertilityIn fact, male sexual function is normal, and being able to complete the "** essence" in a spouse is only one of the prerequisites for normal childbearing. Another important condition is the needSperm quality is normal in males**Male infertility can be divided into:Primary infertilitywithSecondary infertility。Many patients with primary infertility have normal libido, erection and sperm, but there are big problems with the quality of ejaculated sperm, and even suffer from "azoospermia", the sperm quality in such patients is poor or even no sperm, so they cannot complete the effective sperm-egg combination, resulting in infertility. In secondary infertility, even if there has been a history of childbirth, due to acquired factors, such as aging and decreased spermatogenic function, drastic changes in living environment, urinary system diseases, etc., it can also lead to problems with subsequent sperm quality, resulting in fertility difficulties.
**Normal ≠ normal fertility for analysisJust ** routine analysis is normal, does not mean that your fertility is normal, and there are a number of more in-depth examinations about male sperm such as sperm Pap staining, sperm DNA integrity check, etc., to see the male fertility status.
Sperm Pap stainingThe main thing is to check for sperm malformations.
The proportion of sperm in normal form of normal people should be 4%, and when the proportion of abnormal sperm is 96%, it can cause fertility disorders, and even lead to the cessation of the development of the woman's embryo or spontaneous abortion. Microbiology testsIncluding **mycoplasma, chlamydia, common bacteria and other tests.
Microbial infections of the male reproductive system can damage the male reproductive system, affect spermatogenesis, maturation and transportation, resulting in a decrease in quality, causing male infertility, especially the relationship between mycoplasma infection and infertility is becoming more and more important. Detection of sperm acrosome enzyme activity and eliciting sperm acrosome responseSperm acrosome enzymes are present on the inner membrane of the sperm parietal and equatorial membranes, usually in an inactive form, and the acrosomal zymogen is activated as acrosomal enzymes when the sperm head enters the zona pellucida of the egg. The acrosome reaction refers to a series of changes that occur when the sperm meets the egg after the sperm is capacitated.
It generally occurs after the sperm combines with the zona pellucida of the oocyte, and before the sperm penetrates the oocyte membrane and fertilizes the oocyte, which is one of the necessary links for the natural fertilization of the oocyte.
Therefore, even if the sperm motility is high and the number is large, if the sperm acrosome enzyme activity is insufficient or the acrosome response is insufficient, it is still impossible for the woman to conceive naturally. Integrity check of sperm DNASperm DNA integrity test is a new indicator of male fertility, and it is also one of the important reasons for the common impact on male fertility, which is affected by multiple factors such as genetics, environment and life Xi habits, and is closely related to male infertility and spouse's sexual abortion.
The assessment of male fertility and the choice of assisted reproductive technology are of great clinical significance. Studies have found that the degree of DNA damage in infertility patients is significantly higher than that in normal fertility patients.
Sperm DNA integrity is 30% high, which will affect its fertilization rate and clinical pregnancy rate, and may affect embryo development and cause embryo development to stop developing. Sperm has a high rate of DNA fragmentation, which is one of the important factors that lead to male infertility.
I would like to remind all male infertility patientsNeither blind confidence, resist the necessary examination and **, resulting in the delay of the couple's childbearing age, increasing the difficulty and cost of the later stageDon't give up easily**
At present, the combination of internal medicine and surgery has greatly improved the success rate of infertility patients, and is expected to help more infertile families "realize their dreams"!