TMA PEG TMA, Bis PEG TMA can be used as vectors for gene delivery

Mondo Science Updated on 2024-02-01

Product name: TMA-PEG-TMA, BIS TMA-PEG

Chinese name: polyethylene glycol bistrimethylamine salt, trimethylamine salt-polyethylene glycol-trimethylamine salt.

Molecular weight: 1000, 2000, 3400, 5000, 10000, 20000 (can be customized on demand).

End group substitution rate: 95%.

Structural Formula:

Technical indicators: purity (PEG): more than 95%.

Substitution rate (TMA): more than 95%.

Dispersion coefficient (PDI): less than or equal to 105

Appearance: viscous liquid or solid powder, depending on the molecular weight.

Storage conditions: Protect from light, dry, -20 storage.

Precautions: Be sure to dry when taking and avoid frequent dissolution and freeze-drying.

Tips: This reagent is only used for scientific research or industrial applications, and is not medicinal or edible.

Trimethylamine salt-polyethylene glycol-trimethylamine salt is a commonly used chemical reagent that has a wide range of applications in many fields due to its unique properties. First of all, this reagent has good water solubility, so it can be widely used in drug delivery and genetics**. Secondly, due to the stability of its polyethylene glycol chain, this reagent can maintain stability under high temperature, acid-alkali and oxidation conditions, which makes it have a wide range of applications in chemical synthesis and industrial production.

In terms of drug delivery, trimethylamine salt-polyethylene glycol-trimethylamine salt can be used to prepare nano-drug carriers, and the controlled release of drugs can be achieved by encapsulating drug molecules in polymer chains. This nano-drug carrier can improve the bioavailability of drugs, reduce the adverse reactions of drugs, and improve the best effect.

In addition, trimethylamine salt-polyethylene glycol-trimethylamine salt can also be used in genes** as a carrier for gene transmission. By encapsulating the gene in a polymer carrier, the gene is protected from degradation by enzymes and can be accurately delivered to the target cells, resulting in gene precision**.

In terms of chemical synthesis, trimethylamine salt-polyethylene glycol-trimethylamine salt can be used as a stabilizer and catalyst in chemical reactions because it can maintain stability under high temperature, acid-base and oxidation conditions. It can effectively increase the rate and yield of chemical reactions, and can reduce the condition requirements of the reaction, so that some chemical reactions that are difficult to carry out can be realized.

The above content is compiled and shared by Xi'an Kaixin Biotechnology***kls.

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