Product name: VE-PEG-VE, BIS VE-PEG
Chinese name: polyethylene glycol divitamin E, vitamin E - polyethylene glycol - vitamin E
Molecular weight: 1000, 2000, 3400, 5000, 10000, 20000 (can be customized on demand).
End group substitution rate: 95%.
Structural Formula:
Technical indicators: purity (PEG): more than 95%.
Substitution rate (VE): more than 95%.
Dispersion coefficient (PDI): less than or equal to 105
Appearance: viscous liquid or solid powder, depending on the molecular weight.
Storage conditions: Protect from light, dry, -20 storage.
Tips: Be sure to keep the environment dry to avoid frequent dissolution and lyophilization processes. Special reminder that this reagent is only suitable for scientific research or industrial applications and other fields, and it is strictly forbidden to use it for pharmaceutical or food purposes. Vitamin E-polyethylene glycol-vitamin E (TPGS) is a block copolymer composed of vitamin E and polyethylene glycol linked by ester bonds. It is a common solubilizer and emulsifier that is widely used in drug delivery systems, cosmetics, and personal care products.
Vitamin E is a fat-soluble antioxidant that protects cell membranes and biofilms from oxidative damage. Polyethylene glycol is a water-soluble polymer with good film-forming properties and stability. By combining the two, TPGS not only inherits the antioxidant properties of vitamin E, but also has the solubilizing and emulsifying functions of polyethylene glycol.
In drug delivery systems, TPGS can be used as a solubilizer and stabilizer to improve the solubility and stability of the drug, thereby improving the bioavailability and efficacy of the drug. In addition, TPGS can also be used as an emulsifier to prepare microemulsions or nanoemulsions to achieve targeted delivery and controlled-release drug delivery.
In cosmetics and personal care products, TPGS can act as a moisturizer and antioxidant, increasing the moisturizing effect and anti-aging ability of the product. At the same time, TPGS can also be used as a solubilizer and emulsifier to improve the stability and texture of the product.
This article is edited by Xi'an Kaixin Biotechnology***kls.